Table 1

Schedule of events for this prospective cohort study

	ED presentation and initiation of mechanical ventilation	Admit to ICU	ICU day 1	ICU day 2	Day 28
Inclusion/exclusion criteria	X
Demographics	X
Comorbidities	X
Illness severity scores	X
Vitals and laboratory data	X
ED treatment variables	X
ED ventilator data	X
ED sedation data	X
Depth of sedation*	X		X	X
ICU sedation data			X	X
CAM-ICU			X	X
Acute brain dysfunction			X	X
Ventilator-free days					X
Other secondary outcomes					X

*Preferentially assessed with RASS Score; SAS or GCS may also be used, per local institutional procedures.
CAM, confusion assessment method; ED, emergency department; GCS, Glasgow Coma Scale; ICU, intensive care unit; RASS, Richmond Agitation-Sedation Scale; SAS, Riker Sedation-Agitation Scale.