Table 1

Schedule of events for this prospective cohort study

ED presentation and initiation of mechanical ventilationAdmit to ICUICU
day 1
day 2
Day 28
Inclusion/exclusion criteriaX
Illness severity scoresX
Vitals and laboratory dataX
ED treatment variablesX
ED ventilator dataX
ED sedation dataX
Depth of sedation*XXX
ICU sedation dataXX
Acute brain dysfunctionXX
Ventilator-free daysX
Other secondary outcomesX
  • *Preferentially assessed with RASS Score; SAS or GCS may also be used, per local institutional procedures.

  • CAM, confusion assessment method; ED, emergency department; GCS, Glasgow Coma Scale; ICU, intensive care unit; RASS, Richmond Agitation-Sedation Scale; SAS, Riker Sedation-Agitation Scale.