Regression estimates for costs, effects and cost-effectiveness at 3 and 12 months (£2013/2014 sterling) (base case, adjusted for baseline differences)
| Cost, effects or cost-effectiveness | Control | Postal* | Nurse* | Nurse versus postal | ||||
| Mean | (95% CI) | Mean | (95% CI) | Mean | (95% CI) | Mean | (95 % CI) | |
| Costs and effects over 3 months | ||||||||
| Total costs per participant (£) | 108 | (80 to 136) | 123 | (111 to 135) | 244 | (221 to 266) | – | |
| Incremental cost (£) | – | 15 | (−15 to 45) | 135 | (99 to 171) | 120 | (95 to 146) | |
| Total QALYs per participant | 0.1957 | (0.1936 to 0.1978) | 0.1952 | (0.1930 to 0.1974) | 0.1948 | (0.1926 to 0.1970) | – | |
| Incremental* QALYs | – | −0.0005 | (−0.0027 to 0.0016) | −0.0009 | (−0.0031 to 0.0012) | −0.0004 | (−0.0026 to 0.0018) | |
| Incremental daily steps | 692 | (363 to 1020) | 1172 | (844 to 1501) | 481 | (153 to 809) | ||
| Incremental weekly minutes of MVPA in bouts of ≥10 min | 43 | (26 to 60) | 61 | (44 to 78) | 18 | (1 to 35) | ||
| Costs and effects over 12 months | ||||||||
| Total cost per participant (£) | 467 | (365 to 569) | 376 | (307 to 445) | 593 | (473 to 714) | – | |
| Incremental cost (£) | – | −91 | (−215 to 33) | 126 | (−37 to 290) | 217 | (81 to 354) | |
| Total QALYs per participant | 0.842 | (0.832 to 0.853) | 0.838 | (0.827 to 0.849) | 0.836 | (0.824 to 0.847) | – | |
| Incremental QALYs | – | −0.004 | (−0.017 to 0.009) | −0.007 | (−0.020 to 0.007) | −0.002 | (−0.016 to 0.011) | |
| Incremental daily steps | – | 642 | (329 to 955) | 677 | (365 to 989) | 36 | (−227 to 349) | |
| Incremental weekly minutes of MVPA in bouts of ≥10 min | – | 33 | (17 to 49) | 35 | (19 to 51) | 2 | (−14 to 17) | |
| ICER* at 3 months | ||||||||
| Cost per additional QALY (£) | – | Postal dominated by control | Nurse dominated by control | Nurse dominated by postal | ||||
| Cost per additional step count (£) | – | £0.02 | £0.12 | £0.25 | ||||
| Cost per additional minute of MVPA in a bout of ≥10 min (£) | £0.35 | £0.35 | £2.21 | £6.67 | ||||
| ICER* at 12 months | ||||||||
| Cost per additional QALY (£) | – | Postal is less costly but has fewer QALYs. £21 162 saved per QALY lost. | Nurse dominated by control | Nurse dominated by postal | ||||
| Cost per additional step count (£) | – | Postal dominates control | 0.19 | 6.03 | ||||
| Cost per additional minute of MVPA in a bout of ≥10 min (£) | – | Postal dominates control | 3.61 | 109.00 | ||||
ICER, incremental cost-effectiveness ratio; MVPA, moderate to vigorous physical activity; QALY, quality-adjusted life-year; *versus control.