Table 4

HRs for type 2 diabetes complications

	Number of events/subjects at risk	Raw model		Adjusted model
	Number of events/subjects at risk	HR (95% CI)	P values	HR (95% CI)	P values
DKD
FINRISK	147/3932	2.15 (1.27 to 3.62)	4.10×	1.72 (1.01 to 2.93)	0.044
Botnia	91/1380	2.19 (1.003 to 4.79)	0.049	1.80 (0.82 to 3.96)	0.143
Combined	238/5312	2.16 (1.40 to 3.34)	5.00×	1.75 (1.13 to 2.71)	0.013
CHD
FINRISK	640/3710	1.44 (1.07 to 1.95)	0.016	1.40 (1.04 to 1.90)	0.028
H2000	152/761	1.46 (0.74 to 2.82)	0.272	1.46 (0.74 to 2.89)	0.274
Botnia	236/1253	1.18 (0.60 to 2.31)	0.630	1.07 (0.54 to 2.11)	0.840
Combined	1028/5724	1.40 (1.10 to 1.81)	8.50×	1.36 (1.05 to 1.76)	0.019

The FINRISK raw models are adjusted for age, cohort year, geographical area and gender. The Health 2000 Cohort (H2000) raw models are adjusted for age, geographical area and gender. The Botnia raw models are adjusted for age and gender. The adjusted models for diabetic kidney disease (DKD) are adjusted for body mass index (BMI) and hypertension in all cohorts in addition to covariates of the raw model. The FINRISK-adjusted model for coronary heart disease (CHD) is adjusted for HDL and total cholesterol, current cigarette smoking, BMI, hypertension and family history of stroke or myocardial infarction in addition to covariates of the raw model. The H2000-adjusted and Botnia-adjusted models for CHD are adjusted for HDL and total cholesterol, current cigarette smoking, BMI and hypertension in addition to covariates of the raw model.