Table 3

Characteristics and clinical findings of patients with sepsis who had face-to-face GP assessment (n=100), in whom infection was suspected or not suspected

Infection suspected by GP†
Yes (n=57),
n (%)
No (n=43),
n (%)
Age (years), median (IQR)66 (58–77)71 (61–81)*
Female25 (43.9)16 (37.2)
Multimorbidity24 (42.1)14 (32.6)
Source of infection
 Respiratory tract25 (43.9)17 (39.5)
 Urinary tract11 (19.3)7 (16.3)
 Abdominal11 (19.3)10 (23.3)
 Skin/soft-tissue5 (8.8)2 (4.7)
 Other5 (8.8)7 (16.3)
Clinical assessment GP
 Recorded vital signs, mean (SD)2.4 (1.0)1.6 (1.3)**
 Temperature recorded42 (73.7)18 (41.9)*
 Temperature >38.0°C31 (54.4)5 (11.6)**
 Blood pressure recorded39 (68.4)26 (60.5)
 Systolic blood pressure <100 mm Hg11 (19.3)6 (14.0)
 Heart rate recorded42 (73.7)24 (55.8)
 Heart rate >130 beats/min10 (17.5)2 (4.7)
 Respiratory rate recorded13 (22.8)2 (4.7)*
 Respiratory rate >25 breaths/min9 (15.8)2 (4.7)
 Altered mental status9 (15.8)9 (20.9)
 Rigors10 (17.5)4 (9.3)
 Not able to stand8 (14.0)6 (14.0)
 Rapid progression of illness12 (21.1)9 (20.9)
Hospital data
 CRP (mg/L), mean (SD)192 (149)197 (178)
 APACHE II score, mean (SD)20.5 (7.3)24.3 (8.1)
 SOFA score, mean (SD)6.9 (3.6)8.1 (3.3)
 qSOFA score ≥218 (31.6)24 (55.6)
Management and outcome
 Referred to hospital39 (68.4)25 (58.1)
 Delay in hours, median (IQR)1.8 (1.3–10.2)1.6 (1.2–10.7)
 Hospital mortality9 (15.8)18 (41.9)**
  • *P<0.05, **P<0.01.

  • †GP recorded an infection diagnosis or mentioned an infectious diagnosis in the first three differential diagnoses.

  • APACHE II, Acute Physiology and Chronic Health Evaluation II; CRP, C reactive protein; GP, general practitioner; qSOFA, quick Sepsis-related organ failure assessment.