Patient characteristics and outcomes of patients with sepsis with and without prior GP cooperative contact
| Prior GP cooperative contact | ||
| No (n=136) | Yes (n=127) | |
| N (%) | N (%) | |
| Age (years), median (IQR) | 68 (60–78) | 70 (58–78) |
| Female | 60 (44.1) | 54 (42.5) |
| Source of infection | ||
| Respiratory tract | 71 (52.2) | 54 (42.5) |
| Urinary tract | 16 (11.8) | 24 (18.9) |
| Abdominal | 20 (14.7) | 26 (20.5) |
| Skin/soft-tissue | 9 (6.6) | 10 (7.9) |
| Other | 20 (14.7) | 13 (10.3) |
| Comorbidities | ||
| Cardiovascular disease | 32 (23.5) | 41 (32.3) |
| Diabetes | 39 (28.7) | 42 (33.1) |
| Chronic Obstructive Pulmonary Disease | 40 (29.4) | 32 (25.2) |
| Kidney disease | 11 (8.1) | 17 (13.4) |
| Malignancy | 14 (10.3) | 10 (7.9) |
| Immunosuppression | 15 (11.0) | 10 (7.9) |
| Multimorbidity | 48 (35.3) | 50 (39.4) |
| APACHE II score, mean (SD) | 22.7 (7.8) | 22.1 (7.5) |
| SOFA score, mean (SD) | 7.8 (3.0) | 7.4 (3.4) |
| Positive blood culture | 41 (30.1) | 45 (35.4) |
| Clinical signs on admission | ||
| Body temperature >38.0°C | 65 (47.8) | 63 (49.6) |
| Body temperature <36.0°C | 10 (7.4) | 16 (12.6) |
| Heart rate >90 beats/min | 103 (75.7) | 84 (66.1) |
| Systolic blood pressure <100 mm Hg | 36 (26.5) | 40 (31.5) |
| Respiratory rate ≥22 breaths/min | 103 (75.7) | 103 (81.1) |
| Altered mental status | 53 (39.0) | 38 (29.9) |
| qSOFA score ≥2, % | 61 (44.9) | 52 (40.9) |
| Laboratory findings on admission | ||
| CRP (mg/L), mean (SD) | 189 (142) | 186 (158) |
| Creatinine (µmol/L), mean (SD) | 147 (95) | 183 (154) |
| Lactate (mmol/L) mean (SD) | 3.5 (2.6) | 3.6 (2.8) |
| Outcome parameters | ||
| Septic shock | 114 (83.8) | 100 (78.7) |
| Length of ICU stay in days, median (IQR) | 4.9 (2.2–11.9) | 5.8 (2.8–12.6) |
| Length of hospital stay, median (IQR) | 13.4 (7.8–22.6) | 13.6 (9.6–22.5) |
| Hospital mortality | 31 (22.8) | 32 (25.2) |
APACHE II, Acute Physiology and Chronic Health Evaluation II, CRP, C reactive protein; GP, general practitioner; ICU, intensive care unit; qSOFA, quick Sepsis-related Organ Failure Assessment.17