Table 1

Comparison of demographics and clinical data between groups defined by in-hospital clinical outcome in 178 patients with sepsis

CharacteristicsSurvivors
(n=104)
Non-survivors
(n=74)
P values
Age (year)78.0 (60.0–84.0)78.0 (69.0–84.0)0.291
Men67 (64.4)49 (66.2)0.805
Body mass index (kg/m2)23.2 (20.4–26.1)21.7 (18.4–24.2)0.006
Comorbidities
 COPD23 (22.1)9 (12.2)0.088
 Diabetes mellitus26 (25.0)21 (28.4)0.614
 Hypertension47 (45.2)31 (41.9)0.662
 Cerebrovascular disease30 (28.8)15 (20.3)0.194
 Neoplasm18 (17.3)12 (16.2)0.848
 Liver disease5 (4.8)4 (5.4)1.000
 Heart failure20 (19.2)14 (18.9)0.958
 Chronic renal failure18 (17.3)11 (14.9)0.664
Smoking (pack years)0 (0–30.0)0 (0–16.3)0.509
Primary site of infection
 Lung77 (74.0)54 (73.0)0.874
 Abdomen10 (9.6)5 (6.8)0.499
 Urinary tract7 (6.7)6 (8.1)0.728
 Gastrointestinal tract7 (6.7)5 (6.8)1.000
 Other site3 (2.9)4 (5.4)0.452
Community-acquired infection85 (81.7)50 (67.6)0.030
Hypotension22 (21.2)41 (55.4)<0.001
Lactate level (mmol/L)1.8 (1.0–3.4)2.7 (1.5–5.7)0.001
Oliguria8 (7.7)16 (21.6)0.007
Pao2/Fio2 (mm Hg)198.5 (119.3–287.5)152.5 (99.6–210.3)0.006
Serum creatinine (µmol/L)97.0 (68.3–176.3)108.5 (64.0–194.3)0.868
Total bilirubin (µmol/mL)13.1 (9.9–22.3)18.0 (12.5–32.8)0.015
Platelets (×109/L)161.0 (95.8–232.5)123.0 (75.0–204.3)0.067
INR1.2 (1.0–1.4)1.3 (1.1–1.6)0.015
Glasgow Coma Scale15.0 (10.0–15.0)13.0 (10.0–15.0)0.117
SOFA score5.0 (4.0–7.0)9.0 (7.0–11.0)<0.001
APACHE II score16.0 (12.0–22.0)21.0 (17.0–30.0)<0.001
Septic shock21 (20.2)38 (51.4)<0.001
Non-invasive ventilation28 (26.9)24 (32.4)0.426
Intubated36 (34.6)43 (58.1)0.002
Positive blood culture19 (18.3)19 (25.7)0.235
Length of ICU stay (days)12.0 (6.0–22.0)12.0 (3.0–25.0)0.521
Length of hospital stay (days)18.0 (10.0–30.0)13.0 (3.0–25.0)0.009
  • Data are presented as n (%) or median (IQR) unless stated otherwise.

  • APACHE, Acute Physiology and Chronic Health evaluation; COPD, chronic obstructive pulmonary disease; ICU, intensive care unit; INR, international normalised ratio; SOFA, Sequential Organ Failure Assessment.