Table 5

Multivariable adjusted relations of serum Mg and HU in patients with OA (n=962)

Quintiles of serum MgP for trend
Q1 (lowest)Q2Q3Q4Q5 (highest)
Median Mg concentration (mmol/L)0.820.870.910.940.99
Participants (n)200215190168189
HU (%)25.519.113.218.514.8
Model 1*1.00 (reference)0.71 (0.44 to 1.14)0.44 (0.26 to 0.75)0.68 (0.41 to 1.14)0.51 (0.30 to 0.85)0.008
P values0.1570.0020.1440.010
Model 2*1.00 (reference)0.73 (0.45 to 1.20)0.38 (0.22 to 0.67)0.59 (0.35 to 1.02)0.50 (0.29 to 0.87)0.006
P values0.2100.0010.0580.013
Model 3*1.00 (reference)0.68 (0.41 to 1.14)0.33 (0.19 to 0.59)0.52 (0.30 to 0.91)0.39 (0.22 to 0.70)<0.001
P values0.142<0.0010.0220.001
  • Data are adjusted OR (95% CI), unless otherwise indicated.

  • *Model 1 was adjusted for age (continuous data) and gender (male, female); model 2 was adjusted for age (continuous data), Body Mass Index (continuous data), gender (male, female), educational level (high school or above, lower than high school), smoking status (yes, no), activity level (continuous data), alcohol drinking status (yes, no), hypertension (yes, no), diabetes (yes, no) and dyslipidemia (yes, no); model 3 was adjusted based on model 2, with additional factor of estimated glomerular filtration rate (continuous data).

  • HU, hyperuricaemia; Mg, magnesium; n, number; OA, osteoarthritis.