Table 7

HELIX subcohort characteristics

TotalBiBEDENINMAKANCMoBaRHEA
(n=1301)(n=205)(n=198)(n=223)(n=204)(n=272)(n=199)
Age, years, median (IQR)8.1 (6.5; 8.9)6.6 (6.4; 6.8)11 (10; 11)8.8 (8.4; 9.2)6.4 (6.1; 6.8)8.4 (8.2; 8.8)6.5 (6.4; 6.6)
Sex, female (%)45.444.942.946.245.647.844.2
Ethnicity, Caucasian (%)9042.9*99.510010095.6100
Family affluence (%)
  Low10.727.816.815.31.515.1
  Middle38.542.921.239.652.726.8 51.3
  High50.829.377.853.63271.733.7
Maternal smoking during pregnancy,
yes (%)
14.812.223.724.763.421.2
Environmental tobacco smoke, yes (%)34.327.324.831.540.118.869.4
Fruit intake, times/week, median (IQR)9 (6; 18)16 (10; 21)6.6 (3.3; 14)7.5 (3.6; 12)7.3 (3.8; 9.6)8.5 (6.2; 14)14 (8.6; 21)
Vegetable intake, times/week, median (IQR)6.5 (4; 10)6 (4; 10)8.2 (4.4; 11)6 (3; 8.5)6 (3.5; 8.5)6.5 (4; 10)8.5 (6; 14)
Visits to fast food restaurant, take away times/week, median (IQR)0.13 (0.13; 0.5)0.5 (0.13; 1)0.13 (0.13; 0.5)0.13 (0.13; 0.5)0.13 (0; 0.13)0.5 (0.13; 0.5)0.13 (0.13; 0.5)
Moderate to vigorous physical activity,
min/day, median (IQR)
36 (22; 55)42 (32; 62)17 (7.8; 29)26 (17; 44)42 (35; 57)35 (23; 63)49 (36; 61)
Food allergy, yes (%)20.72116.73516.218.815.6
Asthma, yes (%)11.618.520.23.67.811.49.1
Child zBMI (%)
  Underweight/normal weight71.477.173.757.77084.162.8
  Overweight18.815.121.223.620.26.220.6
  Obesity9.97.85.118.69.92.616.6
Conners ADHD symptoms, yes (%)10.19.38.66.615.24.410.8
CBCL, total problems, median (IQR)21 (10; 33)15 (8; 28)26 (16; 37)22 (12; 40)27 (17; 42)9 (5; 17)26 (16; 36)
  • *44.9% of the subcohort BiB population is from South Asian ethnic origin and 12.1% of other ethnicity.

  • ADHD, Attention Deficit Hyperactivity Disorder; BiB, Born in Bradford; CBCL, child  behaviour checklist; EDEN, Étude des Déterminants pré et postnatals du développement et de la santé de l’Enfant; HELIX,  Human Early Life Exposome;  INMA, INfancia y Medio Ambiente; KANC, Kaunus cohort; MoBa, Norwegian Mother and Child Cohort Study; zBMI, age standardized z-score for body mass index.