Variables | Hashimoto’s thyroiditis | Crude HR (95% CI) | Adjusted HR‡ (95% CI) | |||||
No | Yes | |||||||
Event | Person-years | Rate† | Event | Person-years | Rate† | |||
Age, years | ||||||||
≤49 | 33 | 22 137 | 1.49 | 11 | 5670 | 1.94 | 1.30 (1.04 to 1.63)* | 1.29 (0.57 to 2.92) |
50+ | 33 | 7371 | 4.48 | 17 | 1819 | 9.35 | 2.09 (1.56 to 2.80)*** | 2.59 (1.33 to 5.03)*** |
Sex | ||||||||
Female | 58 | 26 916 | 2.15 | 25 | 6847 | 3.65 | 1.69 (1.41 to 2.03)*** | 1.99 (1.63 to 2.44)*** |
Male | 8 | 2592 | 3.09 | 3 | 642 | 4.67 | 1.51 (0.86 to 2.66) | 1.33 (0.63 to 2.79) |
Comorbidity | ||||||||
No | 22 | 18 054 | 1.22 | 7 | 2491 | 2.81 | 2.07 (1.58 to 2.71)*** | 2.29 (1.77 to 2.95)*** |
Yes | 44 | 11 454 | 3.84 | 21 | 4998 | 4.20 | 1.18 (0.92 to 1.50) | 1.38 (1.08 to 1.76)** |
Crude HR, relative HR.
*P<0.05, **p<0.01, ***p<0.001.
†Incidence rate, per 1000 person-years.
‡Adjusted HR: multivariable analysis including age, sex, and comorbidities of hyperlipidaemia, diabetes, liver cirrhosis, hypertension, chronic obstructive pulmonary disease, coronary artery disease, inflammatory bowel disease, hyperthyroidism and hypothyroidism.