Patient characteristics at study entry, stratified by subsequent outcome
| Characteristic | Total population | Went on to receive no advice or treatment | Went on to receive advice only | Went on to receive treatment only | Went on to receive advice and treatment | |||||
| Mean/number | SD/% | Mean/number | SD/% | Mean/number | SD/% | Mean/number | SD/% | Mean/number | SD/% | |
| Total population | 1 08 843 | 100% | 41 868 | 38.5% | 13 269 | 12.2% | 32 578 | 29.9 % | 21 128 | 19.4% |
| Age (years) | 51.9 | 12.9 | 50.0 | 13.8 | 48.6 | 13.3 | 54.7 | 11.8 | 53.2 | 11.4 |
| Sex (% male) | 43 567 | 40.0% | 15 809 | 37.8% | 5443 | 41.0% | 13 054 | 40.1% | 9261 | 43.8% |
| Time in study (years, median (IQR)) | 2.6 | 0.9–5.5 | 4.6 | 2.5– 7.9 | 1.7 | 0.4–4.1 | 1.6 | 0.4–3.8 | 1.2 | 0.2–3.2 |
| Ethnicity | ||||||||||
| White ethnicity | 59 643 | 54.8% | 21 447 | 51.2% | 7554 | 56.9% | 17 939 | 55.1% | 12 703 | 60.1% |
| Black ethnicity | 1527 | 1.4% | 501 | 1.2% | 162 | 1.2% | 458 | 1.4% | 406 | 1.9% |
| South Asian ethnicity | 1356 | 1.2% | 437 | 1.0% | 133 | 1.0% | 487 | 1.5% | 299 | 1.4% |
| Mixed race ethnicity | 9700 | 8.9% | 3691 | 8.8% | 1483 | 11.2% | 2566 | 7.9% | 1960 | 9.3% |
| Other ethnicity | 1041 | 1.0% | 398 | 1.0% | 111 | 0.8% | 321 | 1.0% | 211 | 1.0% |
| Unknown ethnicity | 35 576 | 32.7% | 15 394 | 36.8% | 3826 | 28.8% | 10 807 | 33.2% | 5549 | 26.3% |
| BMI (kg/m2)* | 29.3 | 5.8 | 29.2 | 5.9 | 29.4 | 6.2 | 29.2 | 5.6 | 29.3 | 5.7 |
| Current smoking status | 23 592 | 21.7% | 9555 | 22.8% | 2286 | 17.2% | 7498 | 23.0% | 4253 | 20.1% |
| Alcohol (units per week)† | 12.1 | 14.6 | 11.2 | 12.5 | 15.9 | 19.7 | 10.6 | 13.0 | 13.5 | 16.0 |
| IMD score of 5 (most deprived) | 12 606 | 11.6% | 4217 | 10.1% | 2081 | 15.7% | 3116 | 9.6% | 3192 | 15.1% |
| Systolic BP (mm Hg) | 144.3 | 5.9 | 143.7 | 5.9 | 143.3 | 6.1 | 145.2 | 5.6 | 145.0 | 5.7 |
| Diastolic BP (mm Hg) | 87.3 | 5.8 | 86.9 | 5.9 | 87.1 | 5.9 | 87.5 | 5.7 | 87.7 | 5.7 |
| Mean CVD risk score (mean±SD)‡ | 7.1% | 6.3% | 6.1% | 5.9% | 7.1% | 6.7% | 7.6% | 6.2% | 8.3% | 6.9% |
| Age-defined moderate CVD risk (%)¶ | 41 510 | 38.1% | 14 151 | 33.8% | 3887 | 29.3% | 14 950 | 45.9% | 8522 | 40.3% |
| Statin prescription | 13 426 | 12.3% | 3927 | 9.4% | 1472 | 11.1% | 4608 | 14.1% | 3419 | 16.2% |
| Antiplatelet prescription | 6029 | 5.5% | 1404 | 3.4% | 480 | 3.6% | 2567 | 7.9% | 1578 | 7.5% |
*Missing BMI data (n=46 599).
†Missing alcohol data (n=72 785).
‡Based on previous risk score or QRISK2 score estimated from existing or imputed data.
¶Proportion of men aged ≥55 years and women aged ≥60 years who, according to Morales Salinas et al ,14 should be classified as having moderate cardiovascular risk.
BMI, body mass index; BP, blood pressure; CVD, cardiovascular disease; IMD, Index of Multiple Deprivation.