Table 1

Epidemiological and clinical parameters

VariableValueDistributionNumberComments, reference
WomenMSWMSMWomenMSWMSM
1Initial clinic attendances61%27%12%Beta590 787259 064116 137Clinician survey results
2CT infection6.5%23.3%6.2%Beta38 40160 3627200W14 28 29; MSW14 30; MSM14
3NG infection0.7%3.4%38.1%Beta4136880844 248W14 28 29; MSW14 30; MSM14
4MG infection4.2%12.3%9.3%Beta24 81331 86510 801W14; MSW14 30; MSW14
5TV infection4.4%0.0%0.0%Beta25 995W14 28 29 31; MSW14; MSM estimate
6CT-NG coinfection0.3%2.2%6.2%Beta177256997200W14 28; MSW, MSW14
7CT-MG coinfection1.6%2.8%0.0%Beta94537254W, MSW, MSW14
8CT-TV coinfection0.2%0.0%0.0%Beta1182W14 28 29; MSW14; MSM estimate
9NG-MG coinfection0.6%0.6%1.0%Beta354515541161W, MSW, MSM14
10NG-TV coinfection0.4%0.0%0.0%Beta2363W29; MSW14; MSM estimate
11MG-TV coinfection1.0%0.0%0.0%Beta5908W14; MSW, MSM estimate
12Sensitivity of microscopy for detecting NG40%75%75%UniformEstimate based on published studies and clinical experience8
13Specificity of microscopy for detecting NG100%100%100%UniformEstimate based on published studies and clinical experience8
14Sensitivity of microscopy for detecting TV50%50%50%UniformAssumption based on clinical experience
15Specificity of microscopy for detecting TV100%100%100%UniformAssumption based on clinical experience
16Sensitivity of current NAAT test for CT-NG97%97%97%UniformTypical of best-performing tests currently used23
17Specificity of current NAAT test for CT-NG97%97%97%UniformTypical of best-performing tests currently used23
18Sensitivity of POCTs for CT/NG/MG/TV95%95%95%UniformEstimate based on tests currently available10
19Specificity of POCTs for CT/TV/MG96%96%96%UniformEstimate based on tests currently available10
20Specificity of POCTs for NG98%98%98%UniformEstimate based on tests currently available10
21CT infection—probability of PID16%NormalEstimate based on published studies2
22NG infection—probability of PID16%NormalEstimate based on published studies32
23MG infection—probability of PID4%NormalEstimate based on published studies1
24TV infection—probability of PID0%NormalAssumption
25Microscopy at first attendance84%84%84%UniformAssumption, clinician survey results
26Presumptive treatment for CT50%50%50%NormalEstimate based on clinical practice
27Proportion of MG infections cured by CT treatment67%67%67%UniformEstimate based on published studies9
  • CT, Chlamydia trachomatis; MG, Mycoplasma genitalium; MSM, men-who-have-sex-with-men; MSW, men-who-have-sex-with-women; NAAT, nucleic acid amplification test; NG, Neisseria gonorrhoeae; NGU, non-gonococcal urethritis; PID, pelvic inflammatory disease; POCT, point-of-care test; TV, Trichomonas vaginalis.