Cost differences for SC and POC strategies
| Subgroup | Comparison | QALY difference | Microcosting | Tariff costs | ||
| Cost difference | ICER (£/QALY gained) | Cost difference | ICER (£/QALY gained) | |||
| All | POC A vs SC | 124 | £5 646 309 | £45 516 | −£20 407 228 | Cost-saving |
| POC B vs SC | 94 | £11 783 348 | £125 197 | −£20 076 031 | Cost-saving | |
| POC C vs SC | 335 | £12 254 482 | £36 585 | −£26 451 382 | Cost-saving | |
| POC B vs A | −30 | £6 137 039 | Dominated | £331 197 | Dominated | |
| POC C vs B | 241 | £471 133 | £1956 | −£6 375 350 | Cost-saving | |
| Women | POC A vs SC | 51 | £1 815 921 | £35 608 | −£10 754 668 | Cost-saving |
| POC B vs SC | 21 | £4 731 548 | £222 568 | −£10 613 081 | Cost-saving | |
| POC C vs SC | 185 | £4 163 407 | £22 448 | −£14 705 715 | Cost-saving | |
| POC B vs A | −30 | £2 915 627 | Dominated | £141 587 | Dominated | |
| POC C vs B | 164 | −£5 68 141 | Cost-saving | −£4 092 634 | Cost-saving | |
| MSW | POC A vs SC | 47 | £4 22 715 | £9005 | −£6 702 672 | Cost-saving |
| POC B vs SC | 38 | £2 144 488 | £56 104 | −£6 199 430 | Cost-saving | |
| POC C vs SC | 102 | £1 800 685 | £17 724 | −£8 088 999 | Cost-saving | |
| POC B vs A | −9 | £1 721 773 | Dominated | £503 242 | Dominated | |
| POC C vs B | 63 | −£343 804 | Cost-saving | -£1 889 570 | Cost-saving | |
| MSM | POC A vs SC | 26 | £3 407 672 | £130 508 | −£2 949 888 | Cost-saving |
| POC B vs SC | 35 | £4 907 312 | £141 683 | −£3 263 521 | Cost-saving | |
| POC C vs SC | 48 | £6 290 390 | £131 319 | −£3 656 668 | Cost-saving | |
| POC B vs A | 9 | £1 499 639 | £175 909 | −£313 633 | Cost-saving | |
| POC C vs B | 13 | £1 383 078 | £104 258 | −£393 147 | Cost-saving | |
ICER, incremental cost-effectiveness ratios; MSW, men-who-have-sex-with-women; MSM, men-who-have-sex-with-men; POC, point-of-care; QALY, quality-adjusted life year; SC, standard care.