Table 3

Determinants of adherence to chronic polytherapy

DeterminantsReferenceOR95% CIp Value
Gender of patient(male)0.810.73 to 0.90<0.001
Age group (years)(35–54)55–691.151.01 to 1.310.031
70–840.990.86 to 1.140.904
85+0.420.35 to 0.52<0.001
Discharge ward: cardiology(other)1.561.26 to 1.92<0.001
Length of stay(≤7 days)1.111.01 to 1.230.043
PCI(absence)2.602.32 to 2.92<0.001
EB drug use in the 12 months before admission (≥2 prescriptions)
 β-blockers(absence)1.631.40 to 1.90<0.001
 ACEI/ARBs(absence)1.871.69 to 2.07<0.001
 Statins(absence)1.301.14 to 1.50<0.001
 Antiplatelets(absence)1.030.90 to 1.170.702
Patient comorbidities
 Malignant neoplasms(absence)0.850.72 to 1.010.062
 Disorders of lipoid metabolism/obesity(absence)0.910.75 to 1.110.352
 Haematological diseases(absence)0.690.56 to 0.860.001
 Heart failure(absence)0.890.75 to 1.030.115
 Other cardiac diseases(absence)0.850.72 to 1.000.050
 Cardiac dysrhythmias(absence)0.710.63 to 0.81<0.001
 Cerebrovascular disease(absence)0.870.73 to 1.030.102
 Diseases of arteries and arterioles(absence)0.880.76 to 1.020.090
 Chronic obstructive pulmonary disease(absence)0.710.58 to 0.870.001
 Chronic nephropathies(absence)0.830.67 to 1.020.074
 Gastro-oesophageal haemorrhage(absence)0.540.34 to 0.870.011
General practitioner characteristics
 Gender(male)1.010.90 to 1.130.923
 Age group (years)(34–49)50–540.990.85 to 1.140.853
55–590.850.73 to 0.980.026
60+0.860.73 to 1.010.074
 Organisational arrangement(none)association network group practice1.050.91 to 1.220.485
1.130.98 to 1.300.095
1.141.01 to 1.290.042
  • ARBs, angiotensin receptor blockers; EB, evidence-based; PCI, percutaneous coronary intervention.