Grading the quality of the evidence (adapted from GRADE Working Group, 2004)34
| Strength of evidence | Interpretation |
|---|---|
| High quality | Very confident in the estimate of the effect, and further research is very unlikely to change our confidence. |
| Moderate quality | Moderately confident in the estimate of the effect, but further research may have an important impact on our confidence and may change the estimate. |
| Low quality | Somewhat confident in the estimate of the effect, but further research is very likely to have an important impact on our confidence and will likely change the estimate. |
| Very low quality | Very little confidence in the estimate of the effect as it is very uncertain. |