Table 1

Baseline characteristics of the ACE 1950 cohort

Total
n=3706
Men
n=1899
Women
n=1807
P value
Age63.9±0.763.9±0.763.9±0.60.34
Caucasian ethnicity97.897.498.20.08
Higher education46.450.242.3<0.001
BMI27.2±4.427.7±4.026.6±4.8<0.001
Overweight/obesity (BMI ≥25)67.674.959.8<0.001
Systolic blood pressure, mm Hg138±19139±18137±200.02
Diastolic blood pressure, mm Hg77±1080±1074±9<0.001
Hypertension62.066.057.8<0.001
Myocardial infarction4.37.40.9<0.001
Coronary heart disease7.111.52.4<0.001
Heart failure1.62.30.90.001
Atrial fibrillation4.56.42.4<0.001
Stroke/TIA3.85.02.5<0.001
Diabetes mellitus8.611.65.4<0.001
Reduced eGFR3.93.44.30.16
Hypercholesterolaemia52.650.654.70.01
COPD7.26.97.40.60
Obstructive sleep apnoea6.29.03.2<0.001
Current daily smoking14.513.715.30.19
Current or former daily smoking61.862.261.50.64
Daily moist tobacco (‘snus’)2.23.80.4<0.001
Alcohol
 >14 standard drinks/week2.84.31.2<0.001
 ‘Binge drinking’16.325.36.9<0.001
Physical activity level
 Inactive19.122.515.4<0.001
 Low19.719.719.70.98
 Medium40.334.746.1<0.001
 High21.023.118.80.001
Medication
 Any cardiovascular medication (ATC C)46.150.041.9<0.001
 Diuretics (ATC C03)3.12.93.30.52
 Beta blockers (ATC C07)13.416.79.9<0.001
 Calcium channel blockers (ATC C08)8.19.76.4<0.001
 Agents acting on the renin-angiotensin system (ATC C09)26.930.623.0<0.001
 Lipid-modifying agents (ATC C10)26.229.622.5<0.001
  • Categorical variables are reported as percentages. Continuous variables are presented as mean±SD. P values indicate difference between sexes. Higher education: ≥12 years of formal education.

  • ‘Binge drinking’ is defined as heavy episodic drinking (at least five standard drinks of alcohol) at least once per month. Details for classification of physical activity level are provided in online supplementary table 1. Medication: self-reported cardiovascular medication according to ATC classification.

  • ATC, Anatomical Therapeutic Chemical; BMI, body mass index (kg/m2); COPD, chronic obstructive pulmonary disease; eGFR, estimated glomerular filtration rate; TIA, transient ischaemic attack.