Summary of number and type of single-item and multiitem measurement tools used
| Single-item scales: | |
| Pain on activity: | WOMAC Q1 3.0 VAS ‘pain on walking on a flat surface’ (0–100 mm) (n=11) Pain on walking VAS (0–100 mm) (n=5) Pain on movement VAS (0–100 mm); ambulatory pain (5-point Likert); pain with physical activity VAS 11-point scale (n=2) |
| Pain (not further specified): | Pain VAS (0–100 mm) (n=15) Patients assessment of pain score (0–10); pain scale (0–3); Pain NRS (0–10) (n=11) |
| Standing knee pain | Item 5 WOMAC pain scale (n=1) |
| Global rating (physician/investigator) | Investigator Assessment of Disease Status (n=11) Physicians Global Assessment of Arthritis (n=6) Physician Global Assessment of OA (n=2) Physician Global Assessment of Disease Status (n=2); Investigator Assessed Pain Grade; (Physician) Overall Disease Activity (0–100); Physicians Pain Assessment (4-point LK) (n=3) |
| Global rating (patient) | Patients Global Assessment of Arthritis (n=7) Patient Global Assessment of OA (n=3) Patient Global Assessment of Disease Status (n=4) |
| Multiple-item scales: | |
| Lequesne OA Severity Index (n=5) WOMAC LK3.1 (0–20) (n=3) WOMAC LK Pain subscale (0–25); WOMAC OA Index Questionnaire (n=1); WOMAC knee pain score (0–500) [n=7]; KOFUS (0–14) (n=1) | |
KOFUS, Knee Osteoarthritis Flare-up Score; LK, Likert scale; N, number of included studies; OA, osteoarthritis; VAS, Visual Analogue Scale; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index.