Table 2

The temporal change in the proportion of hospitalised elderly patients taking any PIMs from admission to discharge according to their primary diagnosis for admission. Values are given as numbers (percentages) unless stated otherwise

Primary diagnosis for admissionProportion of patients taking any PIMs*
At admissionAt dischargeReduction rate (95% CI)P values†
Total, n=689330 (47.9)173 (25.1)0.48 (0.41 to 0.53)<0.001
Heart failure, n=15375 (49.0)50 (32.7)0.33 (0.16 to 0.47)<0.001
Pneumonia, n=14175 (53.2)33 (23.4)0.56 (0.43 to 0.66)<0.001
Ischaemic stroke, n=10843 (40.0)27 (25.0)0.37 (0.12 to 0.55)0.001
GI bleeding, n=7134 (47.9)11 (15.5)0.68 (0.47 to 0.80)<0.001
UTI, n=5828 (48.3)13 (22.4)0.54 (0.29 to 0.70)<0.001
COPD or asthma, n=5731 (54.4)20 (35.1)0.35 (0.14 to 0.51)<0.001
ACS, n=5623 (41.1)10 (17.9)0.57 (0.28 to 0.74)<0.001
Epilepsy, n=4521 (46.7)9 (20.0)0.57 (0.30 to 0.74)<0.001
  • *PIMs were defined based on the 2015 American Geriatric Society Beers Criteria.

  • †Comparison of the numbers at admission and at discharge using Fisher’s exact test.

  • ACS, acute coronary syndrome; COPD, chronic obstructive pulmonary disease; GI, gastrointestinal; PIM, potentially inappropriate medication; UTI, urinary tract infection.