Table 3

Incidence rates and HRs of keloid risk in patients with different severity of atopic dermatitis

VariablesNkeloidRateCrude HR (95% CI)Crude HR (95% CI)AdjustedHR* (95% CI)Adjusted HR* (95% CI)
Without atopic dermatitis33 4845321.071.00 (reference)1.00 (reference)
With atopic dermatitis83711633.193.84 (3.17 to 4.66)†3.19 (2.60 to 3.89)†
 Mild5193812.583.10 (2.42 to 3.97)†1.00 (reference)2.54 (1.98 to 3.27)†1.00 (reference)
 Moderate to severe3178824.195.02 (3.93 to 6.42)†1.62 (1.19-2.21)‡4.39 (3.38 to 5.70)†1.73 (1.26 to 2.36)†
  • *Model adjusted for age, gender, urbanisation, concurrent allergic diseases (asthma, allergic rhinitis and allergic conjunctivitis) and relevant comorbidities (hypertension, diabetes mellitus, hyperlipidaemia, chronic kidney diseases, chronic liver disease, chronic obstructive pulmonary disease, stroke, coronary artery disease, mental disorders and alcohol attributed disease).

  • †P<0.001.

  • ‡P=0.002.

  • IRR, incidence rate ratio; PYs, person-years; rate, incidence rate in per 1000 person-years.