Table 1

Differences in FFM personality traits, health and sociodemographic indicators between participants who reported developing ADRs between T1 and T2 versus participants who did not report ADRs at either time point

	No ADRs either at T1 or T2 (n=978)		Reported developing ADRs between T1 and T2 (n=217)		F	df	P values
	M	SD	M	SD	F	df	P values
NEO PI-3 domain scales (T2)
Neuroticism	81.96	21.36	85.99	22.53	6.17	1193	0.013
Extraversion	102.21	23.08	100.54	23.21	0.92	1193	0.337
Openness to experience	97.59	18.10	97.68	17.40	0.00	1193	0.944
Agreeableness	122.21	16.72	121.66	17.95	0.19	1193	0.666
Conscientiousness	125.32	20.06	128.99	18.49	6.10	1193	0.014
Health Indicators
Number of EHIF diagnoses (T1)	4.91	4.18	6.76	5.26	31.55	1193	<0.001
Number of EHIF diagnoses (T2)	4.96	4.36	6.80	5.04	29.61	1193	<0.001
Change in the number of EHIF diagnoses from T1 to T2	0.05	3.94	0.06	5.05	0.00	1193	0.954
Number of medicines taken (T1)	1.20	1.90	1.85	2.30	19.47	1193	<0.001
Number of medicines taken (T2)	2.09	2.52	3.47	3.44	46.34	1193	<0.001
Change in the number of medicines taken from T1 to T2	0.89	2.13	1.62	2.87	18.13	1193	<0.001
BMI (T1)	26.83	5.08	27.27	5.09	1.32	1193	0.251
BMI (T2)	27.81	5.62	28.66	5.69	4.03	1191	0.045
Change in BMI from T1 to T2	0.97	2.59	1.37	2.76	4.11	1191	0.043
Systolic BP (T1)	127.27	17.13	129.46	17.43	2.88	1192	0.090
Systolic BP (T2)	133.29	19.71	136.37	20.56	4.25	1192	0.039
Change in systolic BP from T1 to T2	6.04	19.03	6.83	20.20	0.30	1191	0.584
Diastolic BP (T1)	78.61	10.87	79.08	10.93	0.33	1192	0.564
Diastolic BP (T2)	83.01	11.28	83.52	10.88	0.38	1192	0.539
Change in diastolic BP from T1 to T2	4.40	12.17	4.44	13.06	0.00	1191	0.971
Sociodemographic variables (T1)
Age	46.79	15.57	50.60	13.11	11.23	1193	<0.001