Table 4

Latent class characteristics of 177 453* men and 111 503* women in the NIH-AARP cohort

Model F (favoured model)
Class IClass IIClass IIIClass IVClass V
Stable normal weightNormal weight to overweightNormal weight to obeseOverweight to obeseRapid increase to obese
Men
Number, n (%)120 867 (68.1)44 383 (25.0)6 723 (3.8)4 764 (2.7)718 (0.4)
Mean (SD) BMI at 18 years20.75 (0.01)23.92 (0.02)21.69 (0.04)27.16 (0.09)24.76 (0.2)
Mean (SD) BMI at 35 years23.35 (0.01)26.72 (0.01)30.24 (0.04)26.61 (0.09)37.69 (0.26)
Mean (SD) BMI at 50 years24.66 (0.01)29.12 (0.02)31.34 (0.05)30.95 (0.12)35.01 (0.35)
Mean (SD) entry age, years62.88 (0.01)61.59 (0.03)62.03 (0.06)59.71 (0.07)57.73 (0.18)
Mean (SD) current (at baseline) BMI, kg/m2 25.39 (0.01)30.84 (0.02)29.07 (0.05)35.14 (0.12)30.51 (0.28)
Mean (SD) waist circumference, cm94.38 (0.02)106.23 (0.05)102.73 (0.13)115.24 (0.28)105.91 (0.64)
Smoking, n (%)
 Current11 823 (10)3 761 (8)638 (9)460 (10)106 (15)
 Former67 948 (56)26 898 (61)3 809 (57)3 002 (63)370 (52)
 Never37 149 (31)12 130 (27)2 012 (30)1 110 (23)218 (30)
 Missing3 946 (3)1 594 (4)264 (4)191 (4)24 (3)
Mean (SD) alcohol g/day18.69 (0.13)17.45 (0.21)15.48 (0.56)15.57 (0.69)10.22 (1.14)
Women
Number, n (%)36 311 (32.6)45 832 (41.1)23 544 (21.1)3 898 (3.5)1 918 (1.7)
Mean (SD) entry age, years62.48 (0.03)62.23 (0.02)61.07 (0.03)59.61 (0.09)59.69 (0.12)
Mean (SD) BMI at 18 years19.3 (0.01)20.44 (0.01)22.61 (0.02)29.01 (0.09)23.97 (0.1)
Mean (SD) BMI at 35 years20.26 (0.01)22.53 (0.01)25.51 (0.02)28.38 (0.1)36.92 (0.16)
Mean (SD) BMI at 50 years21.16 (0.01)24.77 (0.01)29.52 (0.03)33.51 (0.13)37.69 (0.2)
Mean (SD) current (at baseline) BMI, kg/m2 21.97 (0.01)26.66 (0.01)32.4 (0.03)37.47 (0.15)34.4 (0.19)
Mean (SD) waist circumference, cm76.19 (0.04)86.66 (0.05)97.82 (0.09)106.29 (0.32)101.96 (0.41)
Smoking, n (%)
 Current5803 (16)5660 (12)2733 (12)495 (13)214 (11)
 Former14 173 (39)18 557 (40)9748 (41)1764 (45)731 (38)
 Never15 313 (42)20 290 (44)10 417 (44)1507 (39)909 (47)
 Missing1022 (3)1325 (3)646 (3)132 (3)64 (3)
Mean (SD) alcohol g/day8.07 (0.1)6.26 (0.08)4.47 (0.11)3.92 (0.29)3.4 (0.48)
Hormone therapy use, n (%)
 Ever13 989 (39)20 206 (44)12 215 (52)2241 (57)1092 (57)
 Never22 322 (61)25 626 (56)11 329 (48)1657 (43)826 (43)
  • *Exclusions include 35 women and 2 men with biologically implausible cancers from classes in proportions (2, 16, 12, 0 and 5) and (1, 0, 0, 1 and 0), respectively.

  • BMI, body mass index; NIH, National Institutes of Health.