Model F (favoured model) | |||||
Class I | Class II | Class III | Class IV | Class V | |
Stable normal weight | Normal weight to overweight | Normal weight to obese | Overweight to obese | Rapid increase to obese | |
Men | |||||
Number, n (%) | 120 867 (68.1) | 44 383 (25.0) | 6 723 (3.8) | 4 764 (2.7) | 718 (0.4) |
Mean (SD) BMI at 18 years | 20.75 (0.01) | 23.92 (0.02) | 21.69 (0.04) | 27.16 (0.09) | 24.76 (0.2) |
Mean (SD) BMI at 35 years | 23.35 (0.01) | 26.72 (0.01) | 30.24 (0.04) | 26.61 (0.09) | 37.69 (0.26) |
Mean (SD) BMI at 50 years | 24.66 (0.01) | 29.12 (0.02) | 31.34 (0.05) | 30.95 (0.12) | 35.01 (0.35) |
Mean (SD) entry age, years | 62.88 (0.01) | 61.59 (0.03) | 62.03 (0.06) | 59.71 (0.07) | 57.73 (0.18) |
Mean (SD) current (at baseline) BMI, kg/m2 | 25.39 (0.01) | 30.84 (0.02) | 29.07 (0.05) | 35.14 (0.12) | 30.51 (0.28) |
Mean (SD) waist circumference, cm | 94.38 (0.02) | 106.23 (0.05) | 102.73 (0.13) | 115.24 (0.28) | 105.91 (0.64) |
Smoking, n (%) | |||||
Current | 11 823 (10) | 3 761 (8) | 638 (9) | 460 (10) | 106 (15) |
Former | 67 948 (56) | 26 898 (61) | 3 809 (57) | 3 002 (63) | 370 (52) |
Never | 37 149 (31) | 12 130 (27) | 2 012 (30) | 1 110 (23) | 218 (30) |
Missing | 3 946 (3) | 1 594 (4) | 264 (4) | 191 (4) | 24 (3) |
Mean (SD) alcohol g/day | 18.69 (0.13) | 17.45 (0.21) | 15.48 (0.56) | 15.57 (0.69) | 10.22 (1.14) |
Women | |||||
Number, n (%) | 36 311 (32.6) | 45 832 (41.1) | 23 544 (21.1) | 3 898 (3.5) | 1 918 (1.7) |
Mean (SD) entry age, years | 62.48 (0.03) | 62.23 (0.02) | 61.07 (0.03) | 59.61 (0.09) | 59.69 (0.12) |
Mean (SD) BMI at 18 years | 19.3 (0.01) | 20.44 (0.01) | 22.61 (0.02) | 29.01 (0.09) | 23.97 (0.1) |
Mean (SD) BMI at 35 years | 20.26 (0.01) | 22.53 (0.01) | 25.51 (0.02) | 28.38 (0.1) | 36.92 (0.16) |
Mean (SD) BMI at 50 years | 21.16 (0.01) | 24.77 (0.01) | 29.52 (0.03) | 33.51 (0.13) | 37.69 (0.2) |
Mean (SD) current (at baseline) BMI, kg/m2 | 21.97 (0.01) | 26.66 (0.01) | 32.4 (0.03) | 37.47 (0.15) | 34.4 (0.19) |
Mean (SD) waist circumference, cm | 76.19 (0.04) | 86.66 (0.05) | 97.82 (0.09) | 106.29 (0.32) | 101.96 (0.41) |
Smoking, n (%) | |||||
Current | 5803 (16) | 5660 (12) | 2733 (12) | 495 (13) | 214 (11) |
Former | 14 173 (39) | 18 557 (40) | 9748 (41) | 1764 (45) | 731 (38) |
Never | 15 313 (42) | 20 290 (44) | 10 417 (44) | 1507 (39) | 909 (47) |
Missing | 1022 (3) | 1325 (3) | 646 (3) | 132 (3) | 64 (3) |
Mean (SD) alcohol g/day | 8.07 (0.1) | 6.26 (0.08) | 4.47 (0.11) | 3.92 (0.29) | 3.4 (0.48) |
Hormone therapy use, n (%) | |||||
Ever | 13 989 (39) | 20 206 (44) | 12 215 (52) | 2241 (57) | 1092 (57) |
Never | 22 322 (61) | 25 626 (56) | 11 329 (48) | 1657 (43) | 826 (43) |
*Exclusions include 35 women and 2 men with biologically implausible cancers from classes in proportions (2, 16, 12, 0 and 5) and (1, 0, 0, 1 and 0), respectively.
BMI, body mass index; NIH, National Institutes of Health.