Overview of pilot trials assessing oral propranolol for treatment or prevention of retinopathy of prematurity (ROP)
| Study | Participants propranolol /controls | Gestational age (weeks) | Birth weight (g) | Dosage propranolol (mg/kg/day) | Duration (day) | Rate ROP intervention propranolol versus controls | Side effects |
| Makhoul et al 14 | 10/10 | 24–28 | 854±240 | 2.0 (3×0.67) | 16.3±6.7 (max 28) | 2/10 versus 4/10 | None |
| Filippi et al 15 | 26/26 | 23–25 26–32 | 691±127 860±244 | 1.0 (4×0.25) 2.0 (4×0.5) | 66±31 (6–90) | 4/25 versus 10/26 | 5/26 hypotension bradycardia bronchospasm |
| Sanghvi et al 16 | 55/54 | 26–32 | 1235±280 | 1.0 (2×0.5) | 32 (7–72) | 13/51 versus 24/51 | None |
| Bancalari et al 12 | 20/27 | 26.6±1.6 | 937±285 | 1.5 (3×0.5) | 58±18 | 2/20 versus 14/27 | None |
| Korkmaz et al 13 | 83/88 | 28.0±2.5 | 885±318 | 2.0 (4×0.5) | No data | 4/83 versus 8/88 | None |
| (all) | 194/205 | 23–32 | 1.0–2.0 | 25/189 versus 60/202 | 5/194 hypotension bradycardia bronchospasm |