Table 2

Pre-ICBT and post-ICBT intervention measures for eight donors or donor candidates

Outcome measuresBefore ICBTAfter ICBTr (pre-ICBT and post-ICBT)Effect size (Hedges’ g)*
M SD M SD
Health-related quality of life (RAND SF-36)†
Physical HRQoL
 Physical Health Composite Score54.134.756.384.10.820.30
 Physical functioning55.504.655.383.10.96−0.01
 Role limitations—physical health problems54.135.355.008.9−0.140.15
 Pain55.636.657.758.10.250.35
 General health perceptions51.005.255.003.90.940.30
Psychological HRQoL
 Mental Health Composite Score51.256.954.252.80.240.61
 Emotional well-being48.887.350.885.90.310.35
 Role limitations—mental health problems49.758.552.638.3−0.200.43
 Social functioning54.634.853.004.20.40−0.39
 Energy51.256.657.507.00.381.02
Anxiety and depression (Hospital Anxiety and Depression Scale)‡
 Depression2.001.91.881.60.630.06
 Anxiety4.002.74.503.00.05−0.24
Fatigue (CIS short version)‡
 Fatigue9.756.49.636.00.930.01
  • n=8.

  • *Effect sizes were presented using negative values indicating a reduction of symptoms.

  • †Higher scores represent better functioning.

  • ‡Higher scores represent more symptoms.

  • CIS, Checklist Individual Strength–Fatigue Scale; HRQoL, health-related quality of life; ICBT, internet-based cognitive-behavioural therapy; RAND SF-36, RAND Short Form-36 Health Status Inventory.