Proof-of-concept outcomes in the comparator cohort compared with the low-friction (LF) cohort
| Comparator cohort | LF cohort | ES (95% CI)* | P values† | |
| (N=90) | (N=131) | |||
| Primary outcome | ||||
| Regrafted (proportion yes (%)) | 6/90 (6.7) | 5/131 (3.8) | 0.56 (0.16 to 1.88) | 0.33 |
| Secondary outcomes | ||||
| Reported graft loss | ||||
| Proportion >0% (%) | 36/90 (40) | 20/131 (15) | 0.27 (0.14 to 0.51) | <0.001 |
| Proportion >5% (%) | 22/90 (24) | 15/131 (11) | 0.40 (0.19 to 0.82) | 0.01 |
| Proportion >10% (%) | 15/90 (17) | 9/131 (7) | 0.37 (0.15 to 0.88) | 0.02 |
| Length of stay (LoS) | ||||
| First inpatient LoS | ||||
| Median (95% CI) | 6 (3–13) | 7 (3–16) | 0 (−2.00 to 1.00)‡ | 0.51 |
| Mean (95% CI)§ | 11.5 (15.4) | 12.2 (14.7) | −0.64 (−4.69 to 3.40) | |
| First inpatient LoS/% BSA | ||||
| Median (95% CI) | 2 (0.9–4) | 2 (1.2–3.3) | 0 (−0.42 to 0.50)‡ | 0.87 |
| Total burn service LoS | ||||
| Median (95% CI) | 33.5 (25.5–69.5) n=88 | 32 (18–51) n=129 | 5 (−2.00 to 12.00)‡ | 0.12 |
↵*For regraft and graft loss, OR and 95% CI are reported. For LoS, median and mean differences with 95% CI are reported. Text highlighted in bold shows 95% CI not crossing 1. Comparator cohort used as control cohort.
↵†P values stem from two-sample proportion tests or Mann-Whitney U-tests.
↵‡CI for generalised Hodges-Lehmann median differences.
↵§Used for cost analysis.
BSA, body surface area; ES, effect size.