Table 4

Association analysis of haplotypes derived from polymorphic sites using genotype data

HaplotypeSNPFrequencyAdjusted OR (95% CI)*P values
rs651821rs662799rs2075291TotalCasesControls
1ACG0.71690.75050.66361.00
2GTG0.21710.19030.25941.64 (1.19–2.28)0.003
3GTT0.05960.05090.07332.19 (1.22–3.95)0.009
Rare†***0.00650.00230.00380.33 (0.05–2.40)0.280
  • *OR was adjusted for age, gender, BMI, smoking status, drinking, systolic blood pressure and diastolic blood pressure.

  • †Haplotypes with frequencies <0.01.

  • BMI, body mass index; SNP, single nucleotide polymorphism.