Table 2
Timetable of study period
| Time point | Study period | |||
| Enrolment | Allocation | Postallocation | ||
| Screening | Day 0 | Day 0 | Day 7 | |
| Enrolment: | ||||
| Eligibility screen | X | |||
| Informed consent | X | |||
| Demographic data | X | |||
| Vital signs | X | X | X | |
| Previous History | X | |||
| Concomitant medication | X | X | X | |
| Physical examination and radiography | X | |||
| Laboratory examination | X | X | ||
| Pattern identification of cough and sputum | X | |||
| Allocation | X | |||
| Interventions: | ||||
| High-dose GHX02 |
| |||
| Standard-dose GHX02 |
| |||
| Placebo |
| |||
| Assessments: | ||||
| BSS | X | X | X | |
| QCSCS | X | X | ||
| LCQ-K-acute | X | X | ||
| Frequency of cough fits |
| |||
| IMOS, IMPSS | X | |||
| Withdrawal rate of patients with exacerbation | X | |||
| Concomitant therapy | X | X | ||
| Adverse events | X | X | ||
| Compliance | X | |||
BSS, Bronchitis Severity Score; IMOS, Integrative Medicine Outcome Scale; IMPSS, Integrative Medicine Patient Satisfaction Scale; LCQ-K-acute, Leicester Cough Questionnaire-Korean version acute; QCSCS, Questionnaire on Clinical Symptoms of Cough and Sputum.