Table 2

Baseline comorbidity information included in the MULTI sTUdy Diabetes rEsearch Consortium

Data sets	Metabolic disease			Cardiac disease					Vascular disease			Pulmonary disease	Kidney disease†	Liver disease	Ageing diseases	Cancer	Depression
Data sets	T2DM	Obesity	Dyslipidaemia	Any	Angina	CAD	CHF	MI	Hypertension	PVD*	Stroke /TIA	Pulmonary disease	Kidney disease†	Liver disease	Ageing diseases	Cancer	Depression
ACCORD	+	+	+	+	+		+	+	+	+	+		+		−		+
AFFIRM	+	+	+	+	+	+	+	+	+	+	+	+	+	+
BARI 2D	+	+	+	+	+		+	+	+	+	+		+
ARIC	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+
JHS	+	+	+	+	+	+	+	+	+	+	+	+	+			+	+
FHS cohort	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+‡
FHS offspring	+	+	+	+	+	+	+	+	+	+	+	+	+		+	+§
FHS Gen3	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+
FOCUS	+		+	+	+	+	+		+	+		+	+		+	+
MRFIT	+	+	+	+	+	+	+	+	+		+	+	+	+		+
ALLHAT	+	+	+	+		+		+	+		+		+
BHS	+	+	+	+		+			+			+	+
CORAL	+	+	+	+	+	+	+	+	+	+	+	+	+			+	+
NGHS	+	+	+						+								+
OMNI heart	+	+	+	−					+		+	+	+			+
POWER-UP	+	+	+	+	+	+		+	+		+	+	+	+		+	+
SPRINT-POP	−	+	+	−					+		−	+	+				+

Dyslipidaemia refers to abnormally elevated cholesterol and/or triglycerides; Ageing diseases=dementia, Alzheimer’s or Parkinson’s; ‘−’=exclusion criteria for the clinical trial.
*Peripheral vascular disease as measured by low Ankle-Brachial Index.
†Kidney disease measured by urine albumin, serum creatinine and potassium, or dialysis.
‡Only lung and thyroid.
§Asked at examination 2.
ACCORD, Action to Control Cardiovascular Risk in Diabetes; AFFIRM, Atrial Fibrillation Follow-Up Investigation of Rhythm Management; ALLHAT, Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial; ARIC, Atherosclerosis Risk in Communities; BARI 2D, Bypass Angioplasty Revascularization Investigation in Type 2 Diabetes; BHS, Bogalusa Heart Study; CAD, coronary artery disease; CHF, congestive heart failure; CORAL, Cardiovascular Outcomes in Renal Atherosclerotic Lesions; FHS, Framingham Heart Study; FOCUS, Functional Outcomes in Cardiovascular Patients Undergoing Surgical Hip Fracture Repair; JHS, Jackson Heart Study; MI, myocardial infarction; MRFIT, Multiple Risk Factor Intervention Trial for the Prevention of Coronary Heart Disease; NGHS, NHLBI Growth and Health Study; OMNI heart, Optimal Macronutrient Intake Trial to Prevent Heart Disease; POWER-UP, Practice Based Opportunities for Weight Reduction Trial at the University of Pennsylvania; PVD, peripheral vascular disease; SPRINT-POP, Systolic Blood Pressure Intervention Trial Primary Outcome Paper; TIA, transient ischaemic attack; T2DM, type 2 diabetes mellitus.