Risk factor | Studies with positive association (n) | Controlled studies (n) | Adjusted for | OR or RR or beta (95% or 99% CI) p values |
Age ≥51 years | 2 (53, 71) | 2 | NA | OR 1.03 (95% CI 1.01 to 1.06) p<0.0167 |
NA | OR 1.238 (95% CI 1.235 to 1.242) p<0.00149 | |||
More than one physician involved in their care | 5 (22, 33, 64, 77, 78) | 3 | NA | Beta 0.7 (95% CI 0.5 to 1.0) p=0.03473 |
Adjusted for age, sex, number of chronic conditions and number or drug consumed | OR 1.39 (95% CI 1.17 to 1.67) p<0.00127 | |||
Adjusted for age and number of prescriber | OR 3.52 (99% CI 3.44 to 3.60)60 | |||
Male general practitioner | 2 (53, 71) | 2 | NA | OR 1.07 (95% CI 1.05 to 1.10) p<0.0167 |
NA | OR 1.206 (95% CI 1.202 to 1.210) p<0.00149 | |||
Frequent changes in prescription | 1 (77) | 1 | NA | Beta 0.4 (95% CI 0.2 to 0.9) p=0.01973 |
Not considering the prescription of other physicians | 1 (77) | 1 | NA | Beta 1.9 (95% CI 1.1 to 3.2) p=0.01373 |
Inconsistency in the information | 1 (77) | 1 | NA | Beta 4.4 (95% CI 1.3 to 14.8) p=0.01373 |
Outpatient clinic visit | 1 (46) | 1 | NA | 1.4 (male 95% CI 1.3 to 1.4) (female 95% CI 1.3 to 1.6)42 |
Family medicine/general practice specialty | 3 (53, 56, 71) | 3 | NA | OR 1.06 (95% CI 1.03 to 1.10) p<0.0167 |
NA | OR 1.267 (95% CI 1.265 to 1.269) p<0.00149 | |||
NA | OR 1.46 (95% CI 1.28 to 1.65) p<0.0552 |
CCI, Charlson Comorbidity Index; IP, inappropriate prescribing; NA, not applicable; PIM, potentially inappropriate medication; PPO, potential prescribing omission; START, Screening Tool to Alert doctors to Right Treatment; STOPP, Screening Tool of Older Person’s Prescriptions.