Summary of gene polymorphism analysis
| Genes | Function | |
| BDNF | Brain-derived neurotrophic factor | Neuronal growth factor linked to the development of psychopathologies (such as anxiety) |
| COMT | Catechol-O-methyltransferase | Involved in stress regulation (catecholamine) |
| NPY | Neuropeptide Y | Role in stress response, circadian rhythms and cardiovascular functions |
| NR3C1 | Glucocorticoid receptor (GR) | GR transcription factor |
| NR3C2 | Mineralocorticoid receptor (MR) | MR transcription factor |
| FKBP5 | FK506 binding protein 5 | Gene encoding cochaperone protein essential in GR signalling |
| SLC6A4 | Sodium-dependent serotonin transporter | Serotonin transporter gene |
| NPS | Neuropeptide S | Peptide involves in anxiety, food intake and sleep quality |
| NPSR1 | Neuropeptide S receptor | Receptor involves in anxiety, food intake and sleep quality |
| CRHR1 | Corticotropin-releasing hormone receptor | Involved in HPA axis regulation |
| DRD2 | Dopamine receptor D2 | G protein-coupled receptor |
| OXT | Oxytocin/neurophysin I prepropeptide | Role in cognition, maternal behaviour and cardiovascular functions |
| HMNCN1 | Hemicentin-1 | Protein involved in postpartum depression |
The chosen single nucleotid polymorphism (SNP) aim to characterise vulnerability and severity of PND as well as stress sensitivity.
HPA, hypothalamo–pituitary–adrenal axis; PND, postnatal depression.