Baseline characteristics of all subjects by the development of chronic kidney disease (CKD)
| The subjects who developed CKD (n=167) | All other subjects (n=9961) | P values | |
| Age (years) | 60.0±0.8 | 51.0±0.1 | <0.001 |
| Sex (male, %) | 134 (80.2%) | 5749 (57.7%) | <0.001 |
| BMI (kg/m 2) | 2 4.7±0.2 | 23.8±0.1 | <0.001 |
| SBP (mm Hg) | 118.9±1.3 | 114.1±0.2 | <0.001 |
| DBP (mm Hg) | 72.5±0.8 | 70.6±0.1 | 0.022 |
| Total cholesterol (mg/dL) | 191.8±2.7 | 192.7±0.3 | 0.733 |
| Triglyceride (mg/dL) | 142.9±5.7 | 122.4±0.7 | <0.001 |
| HDL cholesterol (mg/dL) | 54.1±1.0 | 57.4±0.2 | <0.001 |
| Fasting glucose (mg/dL) | 93.4±1.2 | 92.0±0.2 | 0.248 |
| Haemoglobin A 1c(%) | 5.5 3±0.05 | 5.42±0.01 | 0.023 |
| Albumin (mg/L) | 4.25±0.02 | 4.31±0.01 | 0.001 |
| Haemoglobin (g/dL) | 14.7±0.1 | 14.4±0.1 | <0.001 |
| Urea (mg/dL) | 15.36±0.29 | 13.4 7±0.04 | < 0.001 |
| Creatinine (mg/dL) | 1.09±0.01 | 0.90±0.01 | < 0.001 |
| Uric acid (mg/dL) | 5.9 2±0.11 | 5.15±0.01 | <0.001 |
| eGFR (ml/min per 1.73m2) | 69.9±0.7 | 88.5±0.1 | <0.001 |
| hs-CRP (mg/L) | 0.14±0.02 | 0.11±0.01 | 0.154 |
| FVC (%) | 93.4±0.9 | 95.1±0.1 | 0.076 |
| FEV1 (%) | 100.7±1.2 | 103.1±0.1 | 0.046 |
| FEV1/FVC ratio | 0.77±0.52 | 0.81±0.06 | <0.001 |
| Diabetes mellitus (%) | 14 (8.4 %) | 583 (5.9%) | 0.182 |
| Hypertension (%) | 66 (40.7%) | 1602 (16.1%) | <0.001 |
BMI, body mass index; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; FEV1, forced expiratory volume in 1s; FVC, forced vital capacity; hs-CRP, high-sensitivity C reactive protein; SBP, systolic blood pressure.