McNemar’s analysis of each predictive tool compared against one another in determining the need for escalated care in patients with suspected infection (n=316)
| NEWS >4 | qSOFA | NICE MR and HR | NICE HR | |
| SIRS | 0.2 (P=0.893) | 21.3 (P<0.001) | 25.7 (P<0.001) | 6.63 (P=0.01) |
| NICE HR | 5.9* (P=0.034) | 5.9 (P=0.015) | 8.5 (P=0.004) | – |
| NICE MR and HR | 18.5* (P<0.001) | 1.27 (P=0.259) | – | – |
| qSOFA | 19.3* (P<0.001) | – | – | – |
Values represent row-listed diagnostic tool performed better than column-listed diagnostic tool.
*Represents column-listed diagnostic tool performed better than row-listed diagnostic tool.
A P value of <0.005 is considered significant following Bonferroni correction for multiple analysis.
NEWS, National Early Warning Score; NICE-MR and HR, combined analysis of National Institute of Health and Care Excellence moderate-risk and high-risk criteria; qSOFA, quick Sequential Organ Failure Assessment; SIRS, systemic inflammatory response syndrome