Events per 1000 observation years (n events) | Age-adjusted HR (95% CI) | Risk factor-adjusted* HR (95% CI) | |
Coronary heart disease, all | 10.7 (1004) | ||
Low noise, <75 dB(A) | 9.8 (480) | 1.00 (ref) | 1.00 (ref) |
Medium noise, 75–85 dB(A) | 11.4 (453) | 1.15 (1.01 to 1.31) | 1.13 (0.99 to 1.28) |
High noise, >85 dB(A) | 12.4 (71) | 1.27 (0.99 to 1.63) | 1.22 (0.95 to 1.56) |
P value for trend | P=0.01 | P=0.03 | |
Noise peaks unlikely | 10.2 (622) | 1.00 (ref) | 1.00 (ref) |
Noise peaks maybe | 10.6 (135) | 1.05 (0.87 to 1.26) | 1.04 (0.86 to 1.25) |
Noise peaks likely | 12.1 (247) | 1.19 (1.03 to 1.38) | 1.16 (1.00 to 1.34) |
P value for trend | P=0.03 | P=0.06 | |
Coronary heart disease, subjects ≤65 years | 7.5 (375) | ||
Low noise, <75 dB(A) | 6.7 (174) | 1.00 (ref) | 1.00 (ref) |
Medium noise, 75–85 dB(A) | 8.2 (172) | 1.20 (0.97 to 1.48) | 1.17 (0.94 to 1.44) |
High noise, >85 dB(A) | 9.4 (29) | 1.38 (0.93 to 2.05) | 1.30 (0.88 to 1.93) |
P value for trend | P=0.04 | P=0.09 | |
Noise peaks unlikely | 7.5 (243) | 1.00 (ref) | 1.00 (ref) |
Noise peaks maybe | 6.1 (41) | 0.82 (0.58 to 1.13) | 0.82 (0.59 to 1.14) |
Noise peaks likely | 8.3 (91) | 1.11 (0.87 to 1.41) | 1.07 (0.84 to 1.36) |
P value for trend | P=0.60 | P=0.81 | |
Stroke, all | 5.4 (517) | ||
Low noise, <75 dB(A) | 5.3 (262) | 1.00 (ref) | 1.00 (ref) |
Medium noise, 75–85 dB(A) | 5.4 (220) | 1.02 (0.85 to 1.22) | 1.01 (0.84 to 1.21) |
High noise, >85 dB(A) | 6.0 (35) | 1.16 (0.82 to 1.65) | 1.12 (0.79 to 1.59) |
P value for trend | P=0.51 | P=0.65 | |
Noise peaks unlikely | 5.4 (336) | 1.00 (ref) | 1.00 (ref) |
Noise peaks maybe | 4.5 (59) | 0.83 (0.63 to 1.10) | 0.84 (0.63 to 1.10) |
Noise peaks likely | 5.8 (122) | 1.08 (0.88 to 1.33) | 1.06 (0.86 to 1.30) |
P value for trend | P=0.65 | P=0.82 | |
Stroke, subjects ≤65 years | 2.7 (138) | ||
Low noise, <75 dB(A) | 2.8 (73) | 1.00 (ref) | 1.00 (ref) |
Medium noise, 75–85 dB(A) | 2.5 (54) | 0.89 (0.63 to 1.27) | 0.90 (0.63 to 1.28) |
High noise, >85 dB(A) | 3.5 (11) | 1.26 (0.67 to 2.37) | 1.23 (0.65 to 2.32) |
P value for trend | P=0.97 | P=0.98 | |
Noise peaks unlikely | 2.7 (89) | 1.00 (ref) | 1.00 (ref) |
Noise peaks maybe | 1.8 (12) | 0.65 (0.36 to 1.19) | 0.66 (0.36 to 1.20) |
Noise peaks likely | 3.3 (37) | 1.23 (0.84 to 1.81) | 1.23 (0.83 to 1.80) |
P value for trend | P=0.46 | P=0.47 |
*Age in years, baseline body mass index (<18.5, 25 to <30 and ≥30 compared with 18.5 to <25), baseline diabetes, hypertension and by stratification never/ever smoker and cholesterol in quartiles.
Ref, reference.