Table 2

Pooled OR and 95% (CI) of premenstrual syndrome and any intake of alcohol

	Number of studies	OR (95% CI) Fixed effects	OR (95% CI) Random effects	Ri*	Q test P values
All studies	19	1.31 (1.28 to 1.35)	1.45 (1.17 to 1.79)	0.98	0.0001
Case-control studies	7	1.27 (1.14 to 1.41)	1.66 (1.04 to 2.64)	0.93	0.0001
Cross-sectional studies	11	1.67 (1.60 to 1.74)	1.40 (1.00 to 1.94)	0.98	0.0001
Direct calculations	17	1.31 (1.28 to 1.35)	1.51 (1.22 to 1.88)	0.98	0.0001
Quality score ≥3	10	1.11 (1.07 to 1.14)	1.22 (1.05 to 1.42)	0.90	0.0003
Quality score <3	9	1.73 (1.66 to 1.80)	1.50 (1.03 to 2.20)	0.98	0.0001
Full adjustment	7	1.10 (1.07 to 1.14)	1.18 (1.01 to 1.38)	0.90	0.005
Incomplete adjustment	12	1.70 (1.63 to 1.77)	1.47 (1.07 to 2.03)	0.98	0.0001
Validated exposure	11	1.09 (1.05 to 1.12)	1.09 (0.99 to 1.20)	0.77	0.006
Non validated exposure	8	2.06 (1.96 to 2.16)	1.91 (1.40 to 2.62)	0.96	0.0001
Validated diagnosis	12	1.85 (1.77 to 1.94)	1.38 (0.99 to 1.92)	0.97	0.0001
Non validated diagnosis	7	1.10 (1.07 to 1.14)	1.38 (1.16 to 1.65)	0.95	0.0001
High response rate	5	1.16 (1.05 to 1.28)	1.36 (0.99 to 1.88)	0.86	0.003
Low response rate	14	1.32 (1.29 to 1.36)	1.46 (1.13 to 1.89)	0.98	0.0001
Defined target population	12	1.10 (1.07 to 1.13)	1.20 (1.07 to 1.36)	0.86	0.0001
Undefined target population	7	2.05 (1.95 to 2.15)	1.65 (1.02 to 2.67)	0.99	0.0001
US studies	12	1.63 (1.57 to 1.70)	1.56 (1.17 to 2.08)	0.98	0.0001
Rest of the world	7	1.10 (1.06 to 1.14)	1.24 (0.89 to 1.72)	0.98	0.0001