Table 1

Chronic disease risk stratification and disease targets

Medical conditions

  • Ischaemic heart disease

  • Cerebrovascular accident (ischaemic)

  • Peripheral vascular disease

  • DM with CKD (stage 3–4)

  • Aortic aneurysm

  • Familial hypercholesterolaemia

  • CKD with eGFR <60 mL/min/1.73 m2 or DM (not both)

Estimated 10-year CHD risk*
Risk stratum 		­
­
Very high
(any of the above present)		>20%
(or any of the above present)
High 		10%–20%
­
Medium 		<10%
­
Low
Disease targets
 LDL-C (mmol/L)
 Blood pressure (mm Hg)
 HbA1c (%) 		<2.1
<140/90
<140/80 (with DM)
<7		<2.6
<140/90
<140/80 (with DM)
<7		<3.4
<140/90		<4.1
<140/90

  • *By Framingham Risk Score based on age, smoking status, systolic blood pressure, high-density lipoprotein and total cholesterol levels.

  • CHD, coronary heart disease; CKD, chronic kidney disease; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; HbA1c, haemoglobin A1c; LDL-C, low-density lipoprotein cholesterol.