Participants’ demographic and clinical characteristics
| n | 116 |
| Age, years | 50 (6), range 30–60 |
| Sex, % female | 62 |
| Education, years | 16 (2), range 12–22 |
| Family history of LOAD, % positive | 38 |
| APOE ε4 carriers, % positive | 40 |
| Ethnicity, % white | 68 |
| Subjective complaints, % positive | 44 |
| Laboratory findings | |
| BMI (kg/cm2) | 25 (4), range 18–37 |
| Hypertension, % positive | 14 |
| QUICKI score (unitless) | 0.32 (0.03) |
| Plasma cholesterol/HDL ratio (unitless) | 3.3 (0.8) |
| Plasma homocysteine (µmol/L) | 7.9 (6.2) |
| Lifestyle measures | |
| Mediterranean diet (unitless) | 4.3 (1.9), range 1–8 |
| Physical activity (metabolic equivalent/hour) | 9.8 (6.3), range 1–37 |
| Intellectual activity (unitless) | 3.7 (0.7), range 1.8–4.9* |
Values are mean (SD) unless otherwise specified.
*Data were not available for 20 out of 116 patients.
APOE, apolipoprotein E; BMI, body mass index; HDL, high-density lipoprotein; LOAD, late-onset Alzheimer’s disease; QUICKI, Quantitative Insulin Sensitivity Check Index.