Total, n (%) | Women, n (%) | Men, n (%) |

≥2 diagnoses* 408 994 (78.1%) | 217 823 (82.2) | 191 171 (73.9) |

No of diagnoses* | ||

2 | 26 106 (12.0) | 33 850 (17.7) |

3 | 28 243 (13.0) | 33 515 (17.5) |

4 | 28 274 (13.0) | 30 356 (15.9) |

≥5 | 1 35 200 (62.1) | 93 450 (48.9) |

Median no of diagnoses (IQR)† | 5 (4–8) | 4 (3–7) |

No of diagnoses included | 79 | 73 |

No of clusters | 53 | 15 |

No of clusters with ≥2 diagnoses | 12 | 15 |

Median of diagnoses per clusters (IQR)‡ | 2 (2–4) | 5 (2.5–6) |

No of factors | 9 | 10 |

N of factors with ≥2 diagnoses | 8 | 9 |

Median of diagnoses per factor (IQR)‡ | 5.5 (2.75–7) | 4 (4–5) |

*Two sample test of proportions; all P<0.001.

†Mann-Whitney U test; P<0.001.

‡Median of clusters or factors with ≥2 diseases; P<0.001.