Table 1

Baseline characteristics

Population characteristics (n=532)IrelandSwitzerlandNetherlandsP value
Number of patients, n (% of total population in study)115 (21.6)162 (30.5)255 (47.9)
Mean age (years) (±SD), range74.6 (5.9), 66–9576.4 (5.9), 66–9276.1 (6.8), 66–950.054
Females, n (%)49 (42.6)75 (46.3)166 (65.1)<0.001
Current smokers, n (%)5 (4.3)12 (7.4)24 (9.4)0.02
Mean alcohol consumption (units per week) (±SD)5.5 (9.4)3.6 (4.9)7.4 (10.3)0.008
Living arrangements (co-habiting),* n (%)77 (66.9)91 (56.2)161 (63.1)0.021
Mean body mass index (±SD)28.3 (4.3)27.5 (4.9)27.8 (4.8)0.318
Most common morbidity, hypertension, n (%)75 (65.2)83 (51.2)114 (44.7)0.001
Median number of drugs prescribed per patient, IQR4 (2,5)4 (2,5)4 (2,6)0.828
Polypharmacy,† n (%)51 (44.3)60 (37.0)106 (41.6)0.447
Mean (±SD) EuroQol 5D: EQ Visual Analogue Scale score/10082 (15.2)82 (12.1)76 (11.6)<0.001
Mean (±SD) Mini-Mental State Examination (/30)28 (2.2)28 (1.8)29 (1.2)<0.001
Mean (± SD) ‡TRUST Barthel Index/2222 (1.0)22 (1.0)22 (1.0)0.010
  • *Living arrangements: whether participants were co-habiting or living alone.

  • †Polypharmacy: defined as five or more regular medicines.

  • ‡An extra question was added under the heading ‘Bladder’: ‘does the participant have a urinary catheter?’

  • TRUST, Thyroid Hormone Replacement for Subclinical Hypothyroidism Trial.