Table 2

Results of the univariable and multivariable logistic regression analyses for the association between age, sex, multimorbidity and polypharmacy with potentially inappropriate prescribing

Explanatory variableUnivariable modelP valueMultivariable model*P value
OR (95% CI)OR (95% CI)
Age (years)1.02 (0.99 to 1.06)0.220.99 (0.94 to 1.03)0.54
Females (vs males)1.18 (0.70 to 1.96)0.541.47 (0.84 to 2.59)0.18
Multimorbidity†3.24 (1.93 to 5.44)<0.012.08 (1.16 to 3.73)<0.01
Polypharmacy‡5.52 (3.10 to 9.86)<0.014.81 (2.52 to 9.16)<0.01
  • *Adjusted for age, sex, multimorbidity, polypharmacy and country.

  • †Multimorbidity: defined as the co-occurrence of three or more chronic conditions.

  • ‡Polypharmacy: defined as five or more regular medicines.