Table 2

General characteristics of patients with bronchiectasis with and without PA

ParameterWhole groupPANon-PAP values
Subject, n1188232956
Sex, M/F, n541/64766/166475/481<0.001
Age, years57 (48–64)56 (47–64)57 (49–65)0.133
BMI, kg/m2 21.5 (19.0–23.9)21.4 (3.6)21.5 (19.0–24.0)0.476
Smoking history, n (%)250 (21.0)21 (9.1)229 (24.0)<0.001
Current smokers, n (%)149 (12.5)12 (5.2)137 (14.3)<0.001
Ex-smokers, n (%)101 (8.5)9 (3.9)92 (9.6)0.005
Previous pneumonia, n (%)22 (1.9)7 (3.4)15 (1.6)0.082
Previous tuberculosis, n (%)193 (16.3)36 (15.5)157 (16.5)0.723
Purulent sputum, n (%)851 (71.9)196 (84.5)655 (68.8)<0.001
Haemoptysis, n (%)394 (33.3)94 (40.5)300 (31.5)0.009
Onset of symptoms, years4 (0–19)14 (5–30)3 (0–10)<0.001
Length of hospitalisation, days9 (7–12)9 (7–12)9 (7–12)0.298
mMRC score1 (0–2)1 (0–2)1 (0–1)0.302
LCQ score13 (11–15)11 (9–13)14 (11–16)<0.001
HRCT involvement, U/B, n399/74943/183356/566<0.001
Cystic bronchiectasis, n (%)559 (50.5)171 (79.2)388 (43.5)<0.001
CD4/CD8, %1.8 (1.2–2.5)1.6 (1.2–2.4)1.8 (1.2–2.6)0.101
Normal ABG, %640 (64.0%)112 (48.7%)528 (68.6%)<0.001
IL-1, pg/mL23 (18–32)22 (17–33)23 (18–32)0.485
IL-6, pg/mL36.0 (25.0–55.0)50.0 (29.0–79.0)34.0 (24.0–51.5)<0.001
IFN, KU/L15 (12–21)15 (12–20)15 (12–21)0.989
WBC, 10–9/L6.2 (4.9–8.1)6.9 (5.5–9.1)6.0 (4.8–7.8)<0.001
CRP, IU/mL5.3 (3.0–10.9)6.5 (3.7–20.6)4.7 (2.9–8.9)<0.001
ESR, mm/H28.5 (14.0–55.0)47.0 (23.0–74.0)26.0 (12.0–49.5)<0.001
FVC% of predicted (%)84.9 (67.1–98.8)74.2 (22.8)85.6 (21.1)<0.001
FEV1% of predicted (%)72.8 (49.3–90.6)55.3 (33.4–77.2)75.4 (56.4–92.7)<0.001
FEV1/FVC (%)86.6 (71.2–97.4)75.6 (61.4–91.5)88.3 (74.9–98.1)<0.001
  • Data are presented as n (%) or median (IQR), unless otherwise stated.

  • ABG, arterial blood gas; BMI, body mass index; CRP, C reactive protein; ESR, erythrocyte sedimentation rate; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; IFN, interferon; IL-1, interleukin 1; IL-6, interleukin 6; LCQ, the Leicester Cough Questionnaire; mMRC, modified Medical Research Council; U/B, unilateral/bilateral; WBC, white blood cell.