Risk factors, their corresponding statement in the Drug-Associated Risk Tool (DART) and criteria to evaluate correlation between the answers in DART and objective data
| Risk factor | Corresponding statement in DART | Acceptance criteria for correlation |
| Language issues (eg, migration background) | 1 | No comparison with objective data |
| Polymorbidity: divided in subcategories | ||
| Renal impairment | 2 | Diagnosis of renal impairment and/or GFR <60 mL/min for at least 3 months33 |
| Hepatic impairment | 3 | Diagnosis of hepatic impairment and/or chronic hepatitis and/or hepatic cirrhosis |
| Chronic cardiac disease | 4 | Diagnosis of chronic cardiac disease (heart failure, coronary heart disease, arrhythmias) |
| Chronic respiratory disease | 5 | Diagnosis of asthma or chronic obstructive pulmonary disease |
| Diabetes | 6 | Diagnosis of diabetes mellitus type 1 or 2 or diabetes caused by steroids |
| Cognitive impairment/dementia | 7 | Diagnosis of cognitive impairment or dementia or 25/30 points in the Mini-Mental State Examination34 or <14/20 points in the Micro-Mental Test26 |
| The patient takes medication(s) besides the prescribed ones (eg, over-the-counter, vitamin supplementation) | 8 | No comparison with objective data possible |
| Polypharmacy | 9 | The patient takes more than five medicines when admitted to the hospital |
| Antiepileptic, anticoagulants, non-steroidal anti-inflammatory drugs (NSAIDs), combination of NSAIDs and anticoagulants, digoxin, corticosteroids, diuretics, tricyclic antidepressants, anticholinergic drugs, benzodiazepines, opiates/opioids, oral antidiabetics/insulin, medication with a narrow therapeutic range | 10 | The drug is present on patients’ medication list at hospital admission |
| Non-adherence | 11 | No comparison with objective data24 |
| Earlier experience of adverse drug reactions | 12–16 | Negative total score in both—the statements 12–16 and the Beliefs about Medicines Questionnaire (BMQ)25 or a positive total score in both—the statements 12–16 and the BMQ25 |
| Missing information, partial knowledge of the patient, the patient does not understand the goal of the therapy | 17 | No comparison with objective data |
| Impaired manual skills—causing handling difficulties | 18 | No comparison with objective data |
| Visual impairment/impaired eyesight | 18 | No comparison with objective data |
| Difficult to handle medication | 19 | Medicines for parenteral, transdermal or inhalative application at time of hospital admission |
GFR, glomerular filtration rate.