Table 1

Substances identified

Pharmacological groupsWomen (n)Percentage of womenRecommendations during pregnancy from promedicin.dk*
Analgesics 51 11.7
  Acetaminophen (paracetamol)419.4Can be used if necessary
 Codeine51.1Should not be used
 Ibuprofen20.5Only under certain conditions
 Lidocaine + prilocaine (Emla†)10.2Can be used if necessary
 Morphine (from codeine‡)10.2Should not be used
  Salicylic acid (from acetylsalicylic acid)20.5Only under certain conditions
 Tramadol10.2Only under certain conditions
Antidepressants 13 3.0
 Amitriptyline20.5Can be used if necessary
 Citalopram40.9Can be used if necessary
  Fluoxetine20.5Only under certain conditions
  Sertraline30.7Can be used if necessary
 Venlafaxine 2 0.5Can be used if necessary
Antipsychotics 3 0.7
 Chlorprothixene (first generation, HD)10.2Should not be used
 Quetiapine (second generation)10.2Only under certain conditions
 Risperidone (second generation)10.2Only under certain conditions
Anxiolytics 1 0.2
 Diazepam10.2Only under certain conditions
Antiepileptics 2 0.5
  Gabapentin10.2Should not be used
 Lamotrigine10.2Only under certain conditions
 Levetiracetam10.2Only under certain conditions
 Oxcarbazepine10.2Should not be used
Central stimulators 1 0.2
 Methylphenidate (ritalinic acid)§10.2Should not be used
Antihistamines 8 1.8
 Cetirizine61.4Can be used if necessary
 Cyclizine10.2Only under certain conditions
 Meclozine10.2Only under certain conditions
Antidiabetics 8 1.8
 Metformin81.8Only under certain conditions
Sympathomimetic 1 0.2
  Salbutamol10.2Can be used if necessary
Quinin (possibly from tonic water) 2 0.5 Only under certain conditions
Illegal substances 4 0.9
 Cannabis¶  (THC-COOH and THC-COOH-glucuronide)40.9
 Amphetamine10.2
 Cocaine** (benzoylecgonine, levamisole and phenacetin)10.2
  • *Promedicin.dk is a Danish website developed by Danish Medicine Information for medical doctors and other healthcare personnel and contains detailed information on all marketed human medications. It is the most frequently used source of information on medication safety among Danish health professionals.

  • †Emla is a local anaesthetic containing lidocaine and prilocaine.

  • ‡Morphine was found in a serum sample that also contained codeine, suggesting that the morphine could be a metabolite from codeine.

  • §Ritalinic acid is a metabolite of methylphenidate, indicating the use of methylphenidate.

  • ¶The detected THC-COOH and THC-COOH glucuronide metabolites indicate the use of cannabis.

  • **The detection of the metabolite benzoylecgonine and the ‘cocaine cutting agents’ levamisole and phenacetin indicates cocaine use.