Table 2

Guideline assessment according to the AGREE-II instrument (n=20)

Guideline organisation/society/authorsDomain scores (%)Mean domain scores (%)Agreement between appraisers
Scope and purposeStakeholder involvementRigour of developmentClarity and presentationApplicabilityEditorial independenceWeighted kappa coefficient (κ, 95% CI)
USA
 Wheeler and Acord-Vira34 86.161.153.188.910.445.857.60.93 (0.86 to 1.0)
 Wolf and Nilsen35 94.458.357.366.7029.251.00.74 (0.61 to 0.87)
 DVA/DoD AHA36 86.163.962.5750047.90.75 (0.62 to 0.87)
 Miller et al 41 69.458.39.422.205034.90.94 (0.88 to 1.0)
 Warden et al 42 80.613.930.2500029.10.67 (0.52 to 0.83)
 Weinstein et al 43 27.822.24.238.9079.228.70.64 (0.41 to 0.87)
Australia/New Zealand
 Bayley et al 31 94.466.781.377.868.883.378.70.38 (0.11 to 0.64)
 Stroke Foundation9 10010090.610083.310095.70.90 (0.72 to 1.1)
 NZGG32 91.783.370.883.352.175760.73 (0.52 to 0.95)
 SFNZ and NZGG26 10010089.688.97587.590.20.70 (0.56 to 0.83)
Canada
 ABIKUS40 7555.653.177.80043.60.75 (0.59 to 0.90)
 CSS27 28 10091.787.594.466.710090.00.91 (0.84 to 0.98)
 Khadilkar et al 37 88.952.870.8750047.90.80 (0.68 to 0.91)
 RNAO29 30 10080.567686.170.866.780.00.38 (0.16 to 0.60)
Europe
 ESO38 39 52.830.645.866.70.010049.30.86 (0.75 to 0.96)
 ISWP11 1009791975410089.80.77 (0.62 to 0.91)
 NICE18 91.772.272.966.758.383.374.20.64 (0.39 to 0.89)
 SIGN2 757556.37535.45061.10.46 (0.23 to 0.68)
 SIGN33 91.77589.694.456.325720.62 (0.42 to 0.82)
 SIGN10 97.210087.510010083.394.70.68 (0.36 to 1.0)
  • ABIKUS, Acquired Brain Injury Knowledge Uptake Strategy; AGREE, Appraisal of Guidelines for Research and Evaluation; CSS, Canadian Stroke Strategy; DVA/DoD AHA, Department of Veterans Affairs/Department of Defence American Heart Association; ESO, European Stroke Organisation; ISWP, Intercollegiate Stroke Working Party; NICE, National Institute for Health and Care Excellence; RNAO, Registered Nurses’ Association of Ontario; SFNZ and NZGG, Stroke Foundation of New Zealand and New Zealand Guideline Group; SIGN, Scottish Intercollegiate Guidelines Network.