Factors | Model 1 | Model 2 | Model 3 | ||||||
Coefficient | 95% CI | P value | Coefficient | 95% CI | P value | Coefficient | 95% CI | P value | |
Time | 0.001 | −0.02 to 0.02 | 0.87 | 0.01 | −0.01 to 0.03 | 0.45 | 0.01 | −0.01 to 0.02 | 0.61 |
Time × time | 0.19 | 0.17 to 0.20 | <0.0001 | 0.18 | 0.17 to 0.20 | <0.0001 | 0.18 | 0.17 to 0.20 | <0.0001 |
Baseline age, years | −0.22 | −0.28 to −0.17 | <0.0001 | −0.22 | −0.28 to −0.17 | <0.0001 | −0.22 | −0.28 to −0.17 | <0.0001 |
Gender | −0.13 | −0.28 to 0.03 | 0.11 | −0.18 | −0.34 to −0.02 | 0.003 | −0.18 | −0.34 to −0.02 | 0.03 |
SBP, mm Hg | 0.13 | 0.10 to 0.16 | <0.0001 | 0.08 | 0.04 to 0.11 | <0.0001 | 0.08 | 0.04 to 0.11 | <0.0001 |
DBP, mm Hg | 0.25 | 0.21 to 0.29 | <0.0001 | 0.14 | 0.08 to 0.19 | <0.0001 | 0.14 | 0.08 to 0.20 | <0.0001 |
BMI, kg/m2 | 0.07 | 0.05 to 0.09 | <0.0001 | 0.04 | 0.02 to 0.06 | 0.001 | 0.04 | 0.02 to 0.06 | 0.0003 |
TC, mmol/L | 0.02 | −0.02 to 0.06 | 0.23 | − | − | − | − | − | − |
TG, mmol/L | 0.07 | 0.04 to 0.10 | <0.0001 | 0.02 | −0.01 to 0.06 | 0.25 | − | − | − |
HDL, mmol/L | −0.10 | −0.24 to 0.03 | 0.13 | − | − | − | − | − | − |
FPG, mmol/L | 0.05 | 0.01 to 0.08 | <0.0001 | 0.03 | −0.01 to 0.07 | 0.11 | 0.03 | −0.003 to 0.07 | 0.07 |
SE, dioptre | −0.06 | −0.09 to −0.03 | <0.0001 | −0.04 | −0.07 to −0.02 | 0.003 | −0.04 | −0.07 to −0.01 | 0.003 |
Model 1 is a univariate regression analysis; model 2 is a multiple regression analysis; and model 3 is the optimised model after further excluding the most insignificant variables in model 2 step by step.
BMI, blood mass index; DBP, diastolic blood pressure; FPG, fasting plasma glucose; HDL, high-density lipoprotein cholesterol; IOP, intraocular pressure; SBP, systolic blood pressure; SE, spherical equivalent; TC, total cholesterol; TG, triglyceride; time × time, examination time squared.