Table 1

List of core risk factors for cardiovascular disease (CVD) in the CHinese Electronic health Records Research in Yinzhou (CHERRY) Study

Population census and registered health insurance databaseHealth checks databaseDisease surveillance and management databaseOutpatient/inpatient EMR database (including laboratory testing)Charge and claims databaseEnvironmental monitoring database
Individual-level measurements
 Date of entry of first registration*
 Date of the measurements
 Date of birth, sex and ethnic groups*
 Marital status, education, occupation and socioeconomic status (household income, living space, etc)*
 Smoking and alcohol use (current/former/never; amount/duration, etc)*
 Physical activity*
 Weight, height, waist and hip circumference*
 History of hypertension and diabetes mellitus*
 Prior history of coronary heart disease (in particular myocardial infarction and angina), stroke, transient ischaemic attack (TIA), and peripheral vascular disease (PVD)*
 Family history of diseases*
 Systolic and diastolic blood pressure*
 Metabolic factors (including fasting glucose, postload glucose and glycosylated haemoglobin)
 Lipid profiles: total, high-density and low-density lipoprotein cholesterol; triglycerides (including information about fasting status at time blood samples were taken)
 Blood urea nitrogen, creatinine, uric acid
 Use of cardiovascular medications (including antihypertensive drugs, ‘statins’, fibrates) and other medications (eg, hypoglycaemic agents, hormone replacement therapy)
 Inflammatory markers (including homocysteine, C reactive protein, fibrinogen, albumin, interleukin 6 and the leucocyte count)
 Haemostatic factors (including von Willebrand factor and fibrin D-dimer)
 Novel CVD-related markers (eg, NT-proBNP)
 Cardiovascular imaging information (eg, progression of coronary artery calcium, carotid intima media thickness)
 Urine albumin to creatinine ratio (UACR)
 Cost of outpatient or inpatient admission (including fees for diagnosis, prescription, laboratory test, surgery, etc)
Environmental and ecological data
 Date and region of surveillance
 Air temperature and precipitation
 Particles with aerodynamic diameter <2.5 µm (PM2.5)
 Heavy metal concentration in water (lead, cadmium, mercury and arsenic)
  • * indicates the database has only one record for the measurements.

  • † indicates the database has multiple records for the measurements.

  • Health checks database refers to health checks for new rural cooperative medical scheme, health checks for elderly people, and health checks for adults with hypertension and diabetes in figure 2.

  • EMR, electronic medical record; NT-proBNP, N-terminal pro B-type natriuretic peptide.