Table 4

Presence of investigator financial ties and evaluation of registration quality among positive and negative trials

Study characteristicN (%)P value
Positive trials
n=134
Negative trials
n=58
Financial ties present101 (75)29 (50)*0.001
Financial ties absent33 (25)29 (50)*
Registered at any time130 (97)56 (97)1.0
Registered prospectively94 (70)37 (64)0.39
Prospectively registered with clearly defined primary outcome73 (54)30 (52)0.67
Prospectively registered and published primary outcomes are consistent51 (38)25 (43)0.51
  • *P=0.001.