Table 3

Odds of a prospectively registered outcome consistent with the published outcome on unadjusted analysis and after adjusting for study characteristics

Study characteristicNUnadjusted OR
(95% CI)
Adjusted OR
(95% CI)
Date enrolment began
 Prior to 2006370.04 (0.01 to 0.21)0.05 (0.01 to 0.24)
 2006–2007450.42 (0.18 to 0.99)0.41 (0.18 to 1.00)
 2008–2009630.79 (0.37 to 1.71)0.73 (0.33 to 1.60)
 After 200946
 Study size (per 100 participants)1.03 (1.00 to 1.06)1.0 (0.99 to 1.05)
Investigator financial ties present
 Yes1303.13 (1.57 to 6.22)2.12 (1.00 to 4.51)
 No62