Table 4

Risk difference per 1000 patients of various antibiotics from the network meta-analysis for treatment failure within 1 month

No antibioticsEarly cephalosporinLate cephalosporinTMP-SMXClindamycin
No antibioticsNo antibiotics
Early cephalosporin51 (–34, 226)Early cephalosporin
Late cephalosporin30 (–51, 244)−20 (−109, 100)Late cephalosporin
TMP-SMX −34 (−51, –12) −85 (−260, 4)−64 (−278, 24)TMP-SMX
Clindamycin −39 (−58, –10) −90 (−265, 1)−69 (−283, 22)−6 (−27, 21)Clindamycin
  • Each number is a risk difference, per 1000 patients, and 95% credible interval. The rows are the reference category: a risk difference <0 favours the row. Green shading=high certainty; orange shading=moderate certainty; red shading=low certainty. Based on the median treatment failure rate in the no antibiotics arms, we assume that the baseline risk of treatment failure without antibiotics is 90 per 1000 patients.

  • TMP-SMX, trimethoprim and sulfamethoxazole.