Dose escalation schedule for GaPP2
Day in study | Total number of capsules/day (maximum) | Dosing | Maximum daily dose of gabapentin (mg) |
1 | 1 | One capsule night | 300 |
2 | 1 | One capsule night | 300 |
3 | 1 | One capsule night | 300 |
4 | 2 | One capsule two times a day | 600 |
5 | 2 | One capsule two times a day | 600 |
6 | 2 | One capsule two times a day | 600 |
7 | 3 | One capsule three times a day | 900 |
8 | 3 | One capsule three times a day | 900 |
9 | 3 | One capsule three times a day | 900 |
10 | 4 | One capsule two times+two capsules at night | 1200 |
11 | 4 | One capsule two times+two capsules at night | 1200 |
12 | 4 | One capsule two times+two capsules at night | 1200 |
13 | 5 | Two capsules two times+one capsule once | 1500 |
14 | 5 | Two capsules two times+one capsule once | 1500 |
15 | 5 | Two capsules two times+one capsule once | 1500 |
16 | 6 | Two capsules three times a day | 1800 |
17 | 6 | Two capsules three times a day | 1800 |
18 | 6 | Two capsules three times a day | 1800 |
19 | 7 | Two capsules two times+three capsules night | 2100 |
20 | 7 | Two capsules two times+three capsules night | 2100 |
21 | 7 | Two capsules two times+three capsules night | 2100 |
22 | 8 | Three capsules two times+two capsules once | 2400 |
23 | 8 | Three capsules two times+two capsules once | 2400 |
24 | 8 | Three capsules two times+two capsules once | 2400 |
25 | 9 | Three capsules three times a day | 2700 |
26 | 9 | Three capsules three times a day | 2700 |
27 | 9 | Three capsules three times a day | 2700 |
28–112 | Remain on maximum tolerated dose until the end of week 16 (not exceeding 2700 mg or nine capsules per day). Daily dose should be divided equally into three doses. |
GaPP2, Gabapentin for Pelvic Pain 2.