Risk of prevalent albuminuria and CKD according to quartiles of FLI
| Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | P for trend | ||
| Increased urinary albumin excretion | Model 1 | 1 | 1.34 (1.01 to 1.79) | 1.76 (1.34 to 2.31) | 3.46 (2.70 to 4.44) | <0.0001 |
| Model 2 | 1 | 1.29 (0.97 to 1.72) | 1.66 (1.27 to 2.19) | 3.25 (2.53 to 4.17) | <0.0001 | |
| Model 3 | 1 | 0.94 (0.66 to 1.33) | 1.13 (0.81 to 1.59) | 2.22 (1.60 to 3.07) | <0.0001 | |
| Model 4 | 1 | 0.96 (0.66 to 1.39) | 1.17 (0.77 to 1.77) | 2.30 (1.36 to 3.90) | 0.001 | |
| CKD | Model 1 | 1 | 1.47 (1.13 to 1.90) | 1.79 (1.39 to 2.30) | 3.49 (2.77 to 4.39) | <0.0001 |
| Model 2 | 1 | 1.39 (1.07 to 1.80) | 1.65 (1.28 to 2.12) | 3.16 (2.51 to 3.99) | <0.0001 | |
| Model 3 | 1 | 0.99 (0.73 to 1.36) | 1.03 (0.75 to 1.40) | 1.95 (1.44 to 2.64) | <0.0001 | |
| Model 4 | 1 | 1.00 (0.71 to 1.40) | 1.03 (0.70 to 1.51) | 1.93 (1.18 to 3.15) | 0.012 |
Data are ORs (95% CI). Participants without increased urinary albumin excretion or CKD are defined as 0 and with increased urinary albumin excretion or CKD as 1.
Model 1 is unadjusted.
Model 2 is adjusted for age.
Model 3 is adjusted for age, sex, current smoking status, current drinking status, physical activity, SBP, DBP, LDL-C, fasting insulin, ALT and AST.
Model 4 is adjusted for age, sex, BMI, WC, current smoking status, current drinking status, physical activity, SBP, DBP, TG, LDL-C, fasting insulin, ALT, AST and γ-GGT.
ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; CKD, chronic kidney disease; DBP, diastolic blood pressure; FLI, fatty liver index; FPG, fasting plasma glucose; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure; TG, triglycerides; WC, waist circumference; γ-GGT, γ-glutamyltransferase.