Table 2

Age-dependent linear regression cross-sectional analyses

	Parameter estimates				Model
	β-Estimate	SE	t Value	P value	F	Adj. R²	df	P value
Case–control series
Linear model
All patients
Age:status addicted	−0.4778	0.1768	−2.702	0.0073	6.83	0.0613	3, 265	0.0002
Status addicted	24.8561	11.0893	2.241	0.0258
Quadratic model
Status addicted	0.2634	0.0609	4.326	0.0000	0.0961	6.7000	5, 263	<0.0001
(Age)²:status addicted	3.1664	1.0301	3.074	0.0023
(Age)²	−2.5316	0.8370	−3.025	0.0027
Men
Age:status control	−0.4232	0.2288	−1.85	0.0668	2.6300	0.02524	2, 124	0.0760
Women
Age	−0.0145	0.0038	−3.788	0.0002	9.6000	0.0664	2, 139	0.0001
Age:status addicted	0.0071	0.0021	3.331	0.0011
All patients
Linear model
Status addicted	0.4547	0.0852	5.337	<0.0001	0.0585	33.75	3, 1579	<0.0001
Age:status addicted	−0.0071	0.0016	−4.505	<0.0001
Quadratic model
Status addicted	0.2112	0.0321	6.572	<0.0001	0.0593	20.95	5, 1577	<0.0001
Age:status addicted	−4.1647	1.3631	−3.055	0.00229
Men
Status addicted	0.5628	0.1195	4.709	<0.0001	0.0599	23.52	31, 057	<0.0001
Age:status addicted	−0.0083	0.0019	−4.423	<0.0001
Women
Status addicted	0.1723	0.0400	4.308	<0.0001	0.03261	18.56	1, 520	<0.0001