Construct validity of MRB-QoL subscales
| MRB-QoL subscales | Measures of disease and medicine burden | ||||
| Medical condition (n=338) | Medicine number (n=358) | MRCI (n=277) | DBI (n=262) | CCI (n=292) | |
| Routine and Regimen Complexity | 0.11* | 0.16*** | 0.01 | 0.24*** | −0.19*** |
| Psychological Burden | 0.14*** | 0.11*** | 0.08 | 0.28*** | −0.15*** |
| Functional and Role Limitation | 0.09* | 0.17*** | 0.01 | 0.36*** | −0.23*** |
| Therapeutic Relationship | 0.12* | 0.20*** | −0.16*** | 0.12* | −0.19*** |
| Social Burden | 0.07 | 0.08 | −0.09 | 0.19*** | −0.23*** |
*P<0.05, ***P<0.001.
CCI, Charleston’s Comorbidity Index; DBI, Drug Burden Index; MRB-QoL, Medication-Related Burden Quality of Life; MRCI, Medication Regimen Complexity Index.